- ￥800 - 2500
- 义翘神州
- 40150-D002
- 北京
- 2025年09月11日
- ELISA
- Chimeric
- SARS-COV-2
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- 详细信息
- 用户评价
- 文献和实验
- 技术资料
- 供应商：
北京义翘神州科技股份有限公司
- 库存：
99
- 靶点：
Spike
- 级别：
免疫学试剂
- 目录编号：
40150-D002
- 克隆性：
单克隆
- 抗原来源：
Recombinant SARS-CoV Spike RBD Protein (Catalog#40150-V08B2)
- 保质期：
12个月
- 抗体英文名：
SARS-CoV/SARS-CoV-2 Spike antibody,Chimeric MAb
- 抗体名：
SARS-CoV/SARS-CoV-2 Spike antibody
- 标记物：
Unconjugated
- 宿主：
Chimeric
- 适应物种：
SARS-COV-2
- 免疫原：
SARS-CoV Spike RBD 重组蛋白
- 亚型：
IgG1
- 形态：
液体
- 应用范围：
ELISA
- 保存条件：
-20℃ to -80℃
- 浓度：
ELISA: 1:5000-1:10000
- 规格：
50 µL/100 µL/20 µL
| 规格： | 50 µL | 产品价格： | ￥1500.0 |
|---|---|---|---|
| 规格： | 100 µL | 产品价格： | ￥2500.0 |
| 规格： | 20 µL | 产品价格： | ￥800.0 |
SARS-CoV/SARS-CoV-2 Spike antibody,Chimeric MAb 产品信息
产品名称SARS-CoV/SARS-CoV-2 Spike antibody,Chimeric MAb
经验证的应用ELISA
应用说明IHC, FCM, IF, IP et al. applications haven't been validated. (Antibody's applications haven't been validated with corresponding virus positive samples. Optimal concentrations/dilutions should be determined by the end user.)
特异性SARS Coronavirus spike
Has cross-reactivity in ELISA with
SARS-CoV Spike S1 Protein (Cat# 40150-V08B1)
SARS-CoV-2 (2019-nCoV) Spike S1 Protein (Cat# 40591-V08H)
SARS-CoV-2 (2019-nCoV) Spike RBD Protein (Cat# 40592-V08B)
No cross-reactivity in ELISA with
MERS-CoV Spike S1 Protein (Cat# 40069-V08B1)
HCoV-HKU1 (isolate N1) Spike S1 Protein (Cat# 40021-V08H)
HCoV-HKU1 (isolate N5) Spike S1 Protein (Cat# 40602-V08H)
HCoV-NL63 Spike S1 Protein (Cat# 40600-V08H)
HCoV-229E Spike S1 Protein (Cat# 40601-V08H)
HCoV-OC43 Spike S1+S2 ECD Protein (Cat# 40607-V08B)
免疫原Recombinant SARS-CoV Spike RBD Protein (Catalog#40150-V08B2)
制备方法It is a chimeric monoclonal antibody combining the constant domains of the human IgG1 molecule with mouse variable regions. The variable region was obtained from a mouse immunized with purified, recombinant SARS-CoV Spike RBD Protein. The antibody was produced using recombinant antibody technology.
来源Monoclonal mouse (variable region) / human (kappa / IgG1 constant) chimeric antibody Clone #D002
纯化Protein A
缓冲液0.2 μm filtered solution in PBS
偶联物Unconjugated
状态Liquid
运输方式This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
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文献和实验1, Han H, et al. Rapid field determination of SARS-CoV-2 by a colorimetric and fluorescent dual-functional lateral flow immunoassay biosensor.Sensors and actuators. B, Chemical, PubMed ID: 34658530（文献引用产品货号：40150-D002）
2, Cao J, et al. Screening of Botanical Drugs against SARS-CoV-2 Entry Reveals Novel Therapeutic Agents to Treat COVID-19.Viruses, PubMed ID: 35215943（文献引用产品货号：40150-D002）
3, Yu S, et al. Comparison of Physical and Biochemical Characterizations of SARS-CoV-2 Inactivated by Different Treatments.Viruses, PubMed ID: 36146745（文献引用产品货号：40150-D002）
1, Acharya P, et al. A glycan cluster on the SARS-CoV-2 spike ectodomain is recognized by Fab-dimerized glycan-reactive antibodies.bioRxiv : the preprint server for biology, PubMed ID: 32637953（文献引用产品货号：40150-D001）
2, Akilesh S, et al. Characterizing Viral Infection by Electron Microscopy: Lessons from the Coronavirus Disease 2019 Pandemic.The American journal of pathology, PubMed ID: 33227297（文献引用产品货号：40150-D001）
3, DiMuzio JM, et al. Unbiased interrogation of memory B cells from convalescent COVID-19 patients reveals a broad antiviral humoral response targeting SARS-CoV-2 antigens beyond the spike protein.Vaccine: X, PubMed ID: 33937741（文献引用产品货号：40150-D001）
4, Li D, et al. In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies.Cell, PubMed ID: 34242577（文献引用产品货号：40150-D001）
5, Heggestad JT, et al. Rapid test to assess the escape of SARS-CoV-2 variants of concern.Science advances, PubMed ID: 34860546（文献引用产品货号：40150-D001）
6, Ho TS, et al. Development of SARS-CoV-2 variant protein microarray for profiling humoral immunity in vaccinated subjects.Biosensors & bioelectronics, PubMed ID: 35168024（文献引用产品货号：40150-D001）
7, Jiang Y, et al. Treatment of SARS-CoV-2-induced pneumonia with NAD+ and NMN in two mouse models.Cell discovery, PubMed ID: 35487885（文献引用产品货号：40150-D001）
8, Su WY, et al. Antibody Profiling in COVID-19 Patients with Different Severities by Using Spike Variant Protein Microarrays.Analytical chemistry, PubMed ID: 35442638（文献引用产品货号：40150-D001）
9, Yang Y, et al. Transplacental transmission of SARS-CoV-2 immunoglobulin G antibody to infants from maternal COVID-19 vaccine immunization before pregnancy.Journal of medical virology, PubMed ID: 36367230（文献引用产品货号：40150-D001）
10, Clair LAS, et al. Reduced control of SARS-CoV-2 infection is associated with lower mucosal antibody responses in pregnant women.medRxiv : the preprint server for health sciences, PubMed ID: 36993216（文献引用产品货号：40150-D001）
11, Hora B, et al. Neonatal SHIV infection in rhesus macaques elicited heterologous HIV-1-neutralizing antibodies.Cell reports, PubMed ID: 36924501（文献引用产品货号：40150-D001）
12, St Clair LA, et al. Reduced control of SARS-CoV-2 infection associates with lower mucosal antibody responses in pregnancy.mSphere, PubMed ID: 38426787（文献引用产品货号：40150-D001）
13, Hsieh LL, et al. Bystander monocytic cells drive infection-independent NLRP3 inflammasome response to SARS-CoV-2.mBio, PubMed ID: 39240187（文献引用产品货号：40150-D001）
日前，北京大学生命科学学院魏文胜课题组在 Cell 杂志上在线发表题为“Circular RNA Vaccines against SARS-CoV-2 and Emerging Variants”的研究论文。 魏文胜团队首先建立了体外高效制备高纯度环状 RNA 的技术平台，针对新型冠状病毒及其变异株，设计了编码新冠病毒刺突蛋白（Spike）受体结构域（RBD）的环状 RNA 疫苗。 该项研究中制备的针对新冠病毒德尔塔变异株的环状 RNA 疫苗（circRNARBD
5位院士为代表，超12篇CNS大作，5月新冠研究汇总——全方位围攻新冠病毒，值得收藏
的鸡尾酒疗法也引起了大家的关注，不同的抗体可以识别结合域上不同的抗原表位，在未来的临床应用中能够避免免疫逃逸的理想单克隆抗体对。 5 月 8 日，军事医学科学院生物工程研究所陈薇院士团队和西湖大学周强团队强强联合，在预印本平台 bioRxiv 上线题为：A potent neutralizing human antibody reveals the N-terminal domain of the Spike protein of SARS-CoV-2 as a site
结肠癌（Genentech，Inc.）。VitaxinTM是LM609的人源化形式，直接针对粘附分子v3，正进行III期临床试验治疗各种实体瘤（Ixsys，Inc.，San Diego，CA）。还要进行补充试验考察这两种抗体的安全性和耐受性，以确定其临床应用价值。第三种抗体，c-p1C11是一种针对KDR的IgG1型小鼠/人嵌合抗体，来源于从噬菌体显示文库中分离出的小鼠单链抗体。ELISA和FACS分别证实，c-p1C11能有效地与放射性标记的VEGF竞争性结合细胞表面的KDR，阻断VEGF和KDR的相互
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