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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 英文名：
Saporin
- 供应商：
上海西宝
- 规格：
100 ug
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文献和实验New genes useful in suicide gene therapy are those encoding toxins such as plant ribosome-inactivating proteins (RIPs), which can irreversibly block protein synthesis, triggering apoptotic cell death. Plasmids expressing a cytosolic saporin
Comparison of Immunotoxins Bearing a Single Saporin Molecule with Multiple Toxin Conjugates
Immunotoxins (IT) constructed by conventional chemical means using heterobifunctional crosslinking reagents such as [N -succinimidyl 3-(2-pyridyldithio) propionate (SPDP) or 4-succinimidyloxycarbonyl-α methyl-α-(2-pyridyldithio) toluene (SMPT
a lectin B-chain for cell entry, and thus have a low toxicity for whole cells. Type I RIPs such as saporin can be easily purified (4 ) and have been successfully used to generate potent ITs, displaying antitumor activity both in vitro (5 ) and in vivo (6 ).
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