RUNX2 mouse monoclonal antibod

gene_symbol：RUNX2
predicted_size：54.9 kDa
Uniprot ID：Q1395
description：RUNX2 mouse monoclonal antibody, clone OTI3E12
clonality：Monoclonal
product_type(primary antibody, secondy antibody ,tag antibody,Loding Control...)：Primary Antibodies
background：This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions of potential trinucleotide repeat expansions are present in the N-terminal region of the encoded protein, and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2016]
immunogen：Human recombinant protein fragment corresponding to amino acids 1-293 of human RUNX2 (NP_004339) produced in E.coli.
recommended_dilution：WB 1:1000
predicted_size：54.9 kDa
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
host_species：Mouse
applications：WB
reactivities：Human, Mouse, Rat