【背景知识】 胸腺被理解为一个多功能的调节器官。 除了维持免疫防御[1]的功能外,还描述了对中枢神经系统、内分泌或神经内分泌[2]的影响。 这些作用是通过分泌的单个肽如胸腺素或胸腺素介导的。 胸腺素呈锌复合物的活性形式 [3-5],作用于 T 淋巴细胞及其来自骨髓的祖细胞[6]。 胸腺上皮分泌胸腺素的调节依赖于垂体激素。另一方面,胸腺素在神经内分泌系统中发挥重要作用。 因此,胸腺素的适应症非常多才多艺。
适应症:
免疫疾病或免疫缺陷,例如白血病或艾滋病
自身免疫性疾病,例如 系统性红斑狼疮
类风湿性关节炎、多发性硬化
锌依赖性疾病,例如克罗恩病
内分泌系统疾病
胸腺制剂的质量控制
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