【背景知识】 二胺氧化酶 (DAO) 是组胺的关键内源性降解酶。虽然 DAO 几乎遍布全身,但肠道是其最重要的作用部位。 DAO 的酶活性决定了组胺的降解速率。如果存在 DAO 缺乏或抑制,生物体不能足够快地分解通过食物摄入或从身体自身细胞中释放的组胺,并出现组胺不耐受的症状。数以百万计的人在食用某些食物后会出现胃肠道问题、偏头痛、鼻粘膜刺激和其他类似过敏的症状。体内过多的组胺可能是造成这种广泛症状的原因。 血清中 DAO 浓度 (K 8500) 的测定以及 DAO 活性 (K 8220 DAO REA) 的测定代表了用于鉴别诊断组胺不耐受和相关临床表现的合适标志物。
适应症:
经常头痛或偏头痛
吃含组胺的食物后流鼻涕
组织水肿
眼睑肿胀
皮肤发红
身体疼痛
胃肠道不适
监测无组胺饮食
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