- 询价
- 博湖
- 0.312-20ng/ml
- 进口、国产
- BHE97909
- 2025年07月12日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
100
- 供应商：
上海博湖
- 检测范围：
0.312-20ng/ml
- 检测方法：
Competitive ELISA, Coated with Antigen
- 应用：
0.188ng/ml
- 样本：
ZEB2
- 规格：
96T
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文献和实验Gene Editing in One‐Cell Embryos by Zinc‐Finger and TAL Nucleases
editing using sequence‐specific nucleases. Sequence‐specific nucleases are composed of a domain that binds to the target gene via zinc‐finger or TAL effector‐based DNA recognition motifs. The DNA binding part is fused to the nonspecific nuclease domain
of three-finger chimeric ZFPs. (i) ZFPs composed exclusively of the human zinc fingers described above. We selected eighteen zinc-finger domains after considering each domain's DNA-binding specificity and affinity (see Supplementary Table 1 online). (ii) ZFPs
specificity of each fusion protein was tested by ELISA using a panel of DNA substrates (Fig. 2B,C). The predicted DNA binding site of each TFZF was decoded from the -helical sequence of the corresponding zinc finger (Table 1). As expected, the majority
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