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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
Tankyrase Inhibitors (TNKS) 49
- 库存:
10
- 供应商:
TargetMol
- CAS号:
T23419
- 规格:
50 mg/1 mL/5 mg/100 mg/10 mg
| 规格: | 50 mg | 产品价格: | ¥8583.0 |
|---|---|---|---|
| 规格: | 1 mL | 产品价格: | ¥2643.0 |
| 规格: | 5 mg | 产品价格: | ¥1833.0 |
| 规格: | 100 mg | 产品价格: | ¥13533.0 |
| 规格: | 10 mg | 产品价格: | ¥3183.0 |
Product Introduction
Bioactivity
英文名:Tankyrase Inhibitors (TNKS) 49
描述:Tankyrase Inhibitors 49 is an effective, selective, and orally bioavailable inhibitor of tankyrase (IC50: 0.1nM).

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文献和实验Evaluation of Tankyrase Inhibition in Whole Cells
inhibitors, such as MST-312, whereas pharmacological inhibition of tankyrase 1 enhances telomere shortening by MST-312. These facts indicate that tankyrase 1 could be a target for telomere-directed molecular cancer therapy. Here, the authors
Co-Expression of human DNA primase p49-p58 subunits
Adapted from W.C.Copeland,Protein Exp.& Purif 9,(1997)1-9 and Schneider,et.al.,JBC 273:34 (1998)21608-21615. Obtained from Fanning lab and revised by LSM,7/23/01 Obtained cell stock of BL21(DE3)cells cotransformed with pET21a-Hp49 (ampicillin
三句话读懂一篇 CNS:代糖也有害,增加焦虑风险 | 每天运动仅 3 分钟,死亡风险降低 40%
通讯在 Signal Transduction and Targeted Therapy 杂志发表研究论文 Identification of a class of potent USP25/28 inhibitors with broad-spectrum anti-cancer activity。 该研究筛选了 10 万个合成化合物库,鉴定了一类具有广谱抗癌活性的强效 USP25/28 抑制剂,CT1073 和 CT1113 对于 USP25 和 USP28 具有相似的 KDs,即 CT1073 和 CT
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