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Anti-GABA A Receptor beta 2,3

Chain, extracellular domain of the beta2 & beta3 subunits of the GABA
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  • 询价
  • MAB341
  • 2025年07月16日
  • Immunoprecipitation;Western Blotting
  • Mouse
  • Bovine;Human;Mouse;Monkey
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 应用范围：

      Immunoprecipitation;Western Blotting

    • 宿主：

      Mouse

    • 适应物种：

      Bovine;Human;Mouse;Monkey

    • 库存：

      大量

    • 抗原来源：

      0

    • 是否单克隆：

      1

    • 规格：

      100 μg

    Species Reactivity Key Applications Host Format Antibody Type
    B, H, M, R, Mk, Fe IH, IP, WB Mouse Purified Monoclonal Antibody
    Description:
    Anti-GABA A Receptor β 2,3 Chain, extracellular domain of the β2 & β3 subunits of the GABA A receptor, clone BD17
    Replaces:
    AB5952
    Background Information:
    Gamma-aminobutyric acid type A (GABAA) receptors are members of the neurotransmitter ligand-gated ion channels that mediate neuronal inhibition on binding GABA. The effects of GABA on GABAA receptors are modulated by a range of therapeutically important drugs, including barbiturates, anaesthetics and benzodiazepines.
    Alternate Names:
    • GABA(A) receptor subunit beta-2
    • gamma-aminobutyric acid (GABA) A receptor, beta 2
    • gamma-aminobutyric acid A receptor, beta 2
    Clone:
    BD17
    Specificity:
    Reacts with the β-chain of the GABAA receptor.
    Key Applications:
    • Immunohistochemistry
    • Immunoprecipitation
    • Western Blotting
    Application Notes:
    Immunohistochemistry:
    A 10-20 μg/mL concetration of a previous lot was used in IH.

    Immunoprecipitation:
    A previous lot of this antibody was used in IP.

    Western blot:
    5-20 µg/mL. Recognizes a 55 kDa band corresponding to the beta chain of the GABAA receptor.

    Optimal working dilutions must be determined by end user.
    Species Reactivity:
    • Bovine
    • Human
    • Mouse
    • Rat
    • Monkey
    • Feline
    Species Reactivity Note:
    Expected to react with human and rat based on sequence homology.
    Isotype:
    IgG1
    Immunogen:
    Purified GABA/benzodiazepine receptor from bovine cortex
    Epitope:
    Extracellular domain of the beta2 & beta3 subunits of the GABAA receptor
    Molecular Weight:
    55 kDa
    Control:
    HepG2 cell lysate
    Presentation:
    Purified mouse monoclonal IgG1 liquid in buffer containing 10 mM potassium phosphate buffer pH 7.4 with 150 mM NaCl
    Storage Conditions:
    Stable for 1 year at -20ºC from date of receipt.
    Gene Symbol:
    • GABRB2
    • GABA
    • MGC119388
    • MGC119389
    • MGC119386
    Quality Assurance:
    Evaluated by Western Blot on mouse brain membrane lysates.

    Western Blot:
    1:500 dilution of this antibody detected GABA A Receptor β 2,3 Chain on 10 μg of mouse brain membrane lysates.
    Antibody Category:
    Neuroscience
    Antibody Sub-Category:
    Neurotransmitters & Receptors
    Usage Statement:
    Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    Trade Name:
    Chemicon (Millipore)
    Concentration:
    1.0 mg/mL
    Antibody Type:
    Monoclonal Antibody
    Format:
    Purified
    Host:
    Mouse

    更多产品技术资讯，请访问密理博中国博客：http://blog.milliporechina.com

    Purified GABA/benzodiazepine receptor from bovine cortex. 详细描述见链接：http://www.millipore.com/catalogue/item/MAB341

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