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- 保存条件:
4°C, sealed storage, away from moisture and light
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
55084-08-7
- 规格:
1 mg/5 mg/10 mg/25 mg
| 规格: | 1 mg | 产品价格: | ¥780.0 |
|---|---|---|---|
| 规格: | 5 mg | 产品价格: | ¥1900.0 |
| 规格: | 10 mg | 产品价格: | ¥2813.0 |
| 规格: | 25 mg | 产品价格: | ¥4738.0 |
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Skullcapflavone II
CAS No. : 55084-08-7
MCE 国际站:Skullcapflavone II
产品活性:Skullcapflavone II 是从黄芩中提取的黄酮类化合物,具有抗炎、抗菌作用。Skullcapflavone II 调节破骨细胞的分化、存活和功能。Skullcapflavone II 对 M. aurum 和M. bovis BCG 具有较强的抗菌活性。
研究领域:Anti-infection
作用靶点:Bacterial
In Vitro: Skullcapflavone II inhibits osteoclastogenesis with decreased activation of MAPKs, Src, and cAMP response element-binding protein (CREB), which have been known to be redox sensitive. Skullcapflavone II decreases reactive oxygen species by scavenging them or activating nuclear factor-erythroid 2-related factor 2 (Nrf2), and its effects were partially reversed by hydrogen peroxide cotreatment or Nrf2 deficiency.
In Vivo: Skullcapflavone II, a potential bradykinin antagonist, reduces the major pathophysiological features of allergic asthma, at least in part by acting on TGF-β1/Smad signaling pathways.
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杀伤细胞凝集素样受体G1期( KLRG1 )是II型跨膜糖蛋白抑制性受体,属于C型凝集素样家族。KLRG1以单体和二硫键连接的二聚体形式存在。KLRG1四聚体可作为一个独特的工具用来阐明钙黏着蛋白和KLRG1在免疫调节反应和保持组织完整性过程中发挥的作用。0:00 KLRG1四聚物的合成方法 0:08 内容简介 0:21 内容订阅 0:33 制备包含体 3:07 KLRG1重折叠 4:41 重折叠KLRG1四聚物的浓缩和纯化 6:25 分子排阻层析纯化重折叠KLRG1 6:58
豪斯 请问版内高手一个问题,目前有哪些机制可以在上游调节miR,有没有相关的文献,谢谢 LoftyMan 基本的就是RNA polymerase II吧,其他的一开始分为cellular和viral好学习一些 这么火爆的话题,在Nature搜索一下microRNA的Review就行了,08年Bryan R. Cullen有一篇,最近他又有一篇新的 所谓上游的调控,这个问题我觉得可能比发现miRNA的新
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