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- 英文名:
PrP 106-126 (human)
- 库存:
货期:电询
- 供应商:
MedChemExpress LLC
- 规格:
电询
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Prion Protein 106-126 (human)
CAS No. : 148439-49-0
MCE 国际站:Prion Protein 106-126 (human)
产品活性:Prion Protein 106-126 (human) 是 Prion 的多肽片段,它可以诱导神经元凋亡,抗蛋白酶 K 消化,纤维形成,并介导正常细胞病毒蛋白 (PrPc) 转化为致病同工型 (PrPSc)。Prion Protein 106-126 (human) 通常用作研究朊病毒蛋白疾病中神经变性的模型。
研究领域:Apoptosis
作用靶点:Apoptosis
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文献和实验Secondary structure of prion mRNA
of structural elements in mRNA of prion protein From the EMBL data bank, 23 PrP mRNA sequences of the following species were available: three rodents (mouse, hamster, rat), two ruminants (cattle, sheep), the human and 17 non-human primates consisting
A Function for the Prion Protein
opportunities to consider protein function in relation to the disease phenotype arose (5 ). The identification of the prion gene on chromosome 2 of the mouse (chromosome 20 in the human) (6 ), and the determination of its sequence (7 ), led to the translation
Prion Protein Peptide: Agents of Death for Neurons
occurs comes from studies with scrapie-infected mice, most of the insights regarding a possible mechanism have come from cell culture models in which a synthetic peptide (PrP106-126), based on the sequence of the prion protein, has been applied
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