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- 详细信息
- 技术资料
- 保存条件:
polypeptide, stored under nitrogen, away from moisture
- 英文名:
Neurokinin P TFA
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
148470-19-3
- 规格:
1 mg/5 mg/10 mg/25 mg
| 规格: | 1 mg | 产品价格: | ¥500.0 |
|---|---|---|---|
| 规格: | 5 mg | 产品价格: | ¥1100.0 |
| 规格: | 10 mg | 产品价格: | ¥2000.0 |
| 规格: | 25 mg | 产品价格: | ¥3500.0 |
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Substance P TFA
CAS No. : 148470-19-3
MCE 国际站:Substance P TFA
产品活性:Substance P TFA (Neurokinin P TFA) 是一种神经肽,在中枢神经系统中作为神经递质和神经调节剂。Substance P 的内源性受体是神经激肽1受体 (neurokinin 1 receptor,NK1R)。
研究领域:GPCR/G Protein | Neuronal Signaling
作用靶点:Neurokinin Receptor
In Vitro: The neuropeptide substance P (SP) that are mediated by the neurokinin 1 receptor (NK1-R) desensitize and resensitize, which may be associated with NK1-R endocytosis and recycling. SP and the NK1-R are internalized into the same clathrin immunoreactive vesicles, and then sorted into different compartments. SP is intact at the cell surface and in early endosomes, but slowly degraded in perinuclear vesicles. SP induces clathrin-dependent internalization of the NK1-R. The SP/NK1-R complex dissociates in acidified endosomes. SP is degraded, whereas the NK1-R recycles to the cell surface. SP induces internalization of the NK1-R both in transfected epithelial cells.
相关产品:Drug Repurposing Compound Library Plus | Clinical Compound Library Plus | Bioactive Compound Library Plus | Peptide Library | Substance P | Aprepitant | Fezolinetant | Netupitant | Senktide | Rolapitant | Pavinetant | Neurokinin A TFA | Saredutant | L-732138 | Fosaprepitant dimeglumine | Vapreotide | Maropitant | SB-222200 | Talnetant | Neurokinin B TFA | Vofopitant dihydrochloride | Tradipitant | Eprazinone dihydrochloride | Hemokinin 1 (mouse) | NKP608 | Men 10376 TFA | Osanetant | Y1 receptor antagonist 1 | Elinzanetant | [Sar9,Met(O2)11]-Substance P TFA | Casopitant mesylate | Neurokinin A(4-10) TFA
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