(E/Z)-GSK5182,2699724-40-6

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(E/Z)-GSK5182

CAS No. : 2699724-40-6

MCE 国际站：(E/Z)-GSK5182

产品活性：(E/Z)-GSK5182 是 (E)-GSK5182 和 (Z)-GSK5182 的消旋体。GSK5182 是一种高效选择性，具有口服活性的 ERRγ 反向激动剂，其 IC₅₀ 值为 79 nM。GSK5182 还能增加肝癌细胞中 reactive oxyen species (ROS) 的产生。

研究领域：Vitamin D Related/Nuclear Receptor  |  Metabolic Enzyme/Protease  |  Immunology/Inflammation  |  NF-κB

作用靶点：Estrogen Receptor/ERR  |  Reactive Oxygen Species

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