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Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
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货期:1-2天
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MedChemExpress LLC
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10 mM * 1 mL/5 mg/10 mg/25 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥1490.0 |
|---|---|---|---|
| 规格: | 5 mg | 产品价格: | ¥1350.0 |
| 规格: | 10 mg | 产品价格: | ¥2200.0 |
| 规格: | 25 mg | 产品价格: | ¥4500.0 |
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TIE-2/VEGFR-2 kinase-IN-1
CAS No. : 453590-24-4
MCE 国际站:TIE-2/VEGFR-2 kinase-IN-1
产品活性:TIE-2/VEGFR-2 kinase-IN-1 用于合成 TIE-2 或者 VEGFR-2 抑制剂,从专利 WO2003022852 中获得,例 14。TIE-2/VEGFR-2 kinase-IN-1 用于研究不适当的血管生成相关疾病。
研究领域:Protein Tyrosine Kinase/RTK
In Vitro: Angiopoieten 1 is a ligand for the endotheiium-specific receptor tyrosine kinase, TIE-2 is a novel angiogenic factor.
Inhibition of TIE-2 is expected to serve to disrupt remodeling and maturation of new vasculature initiated by angiogenesis thereby disrupting the angiogenic process. Inhibition at the kinase domain binding site of VEGFR-2 would block phosphorylation of tyrosine residues and serve to disrupt initiation of angiogenesis.
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文献和实验pengchen628 各位前辈现有一个问题请教。 我是将Tie2/LacZ小鼠的骨髓单个核细胞移植到FVB小鼠身上,现在骨髓移植已经成功。我想鉴定FVB小鼠身上是否有LacZ基因,应该采取什么方法? 注:转基因的Tie2/lacZ小鼠可以在内皮细胞专有启动因子Tie2的转录调控下持续表达β-半乳糖苷酶,可与X-gal染色成蓝色,被广泛用于细胞谱系分析。 十分感谢! wbald 你都已经说了,X-gal
). Coordinates for all “potential” systems will lie on a tie-line; the tie-line connects two nodes on the binodal, which represent the final concentration of phase components in the top and bottom phases. Moving along the tie-line coordinates denote systems
a look from the following website just by clicking "Tyrosine Phosphorylation and Dimerization" http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WSN-43F85YV-2&_user=1111158&_coverDate=06%2F29%2F2001&_rdoc=1&_fmt=full&_orig=search
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