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Vonafexor
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Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month.
EYP001
货期:1-2天
MedChemExpress LLC
10 mM * 1 mL/5 mg/10 mg/25 mg/50 mg/100 mg
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CAS No. : 1192171-69-9
MCE 国际站:Vonafexor
产品活性:Vonafexor (EYP001) 是一种具有口服活性和选择性的非甾体 FXR 激动剂。 Vonafexor 与 Peg-IFNα 联合使用,可显著降低 HBsAg。Vonafexor 可用于抗 HBV 的研究。
研究领域:Metabolic Enzyme/Protease | Anti-infection
作用靶点:FXR | HBV
In Vitro: Vonafexor (EYP001) inhibits the HBV replication cycle in HepaRG cells resulting in significant reductions in HBV DNA, HBsAg and HBeAg secretion, with additive effects when combined with Entecavir (HY-13623) or Tenofovir (HY-13910).
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