Cefaloglycin,3577-01-3

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Cefaloglycin

CAS No. : 3577-01-3

MCE 国际站：Cefaloglycin

产品活性：Cefaloglycin (Cephaloglycin) 是一种具有口服活性的肾毒性 β-内酰胺类 (β-lactam) 头孢菌素抗生素，具有抗菌活性。Cefaloglycin 对肠球菌以外的革兰氏阳性球菌 (Gram-Positive cocci) 有活性。Cefaloglycin 对线粒体底物的摄取和呼吸也具有毒性。

研究领域：Anti-infection

作用靶点：Bacterial

In Vitro: Cefaclor to be comparable to Cephaloglycin in terms of in vitro activity against S. pyogenes and somewhat superior to Cephalexin.

In Vivo: Respiration with and the uptake of succinate and ADP are measured in rabbit renal cortical mitochondria exposed for 2 to 6 h to 300 to 3,000 µg of Cefaloglycin (Cephaloglycin) per mL and then washed to remove the antibiotic. Cefaloglycin (Cephaloglycin) irreversibly reduces both respiration and succinate uptake. The pattern of in vitro injury of Cefaloglycin to mitochondrial substrate uptake and respiration evolves in a time-dependent and concentration-dependent manner.

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