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- 文献和实验
- 技术资料
- 靶点:
G9a
- 浓度:
1 mg/mL
- 应用范围:
WB,IHC-P
- 宿主:
Rabbit
- 适应物种:
Human
- 保质期:
1年
- 供应商:
Huabio
- 标记物:
Non-conjugated
- 保存条件:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 形态:
Liquid
- 亚型:
IgG
- 免疫原:
Synthetic peptide within C-terminal human G9A.
- 规格:
50μl/100μl
| 规格: | 50μl | 产品价格: | ¥1500.0 |
|---|---|---|---|
| 规格: | 100μl | 产品价格: | ¥2500.0 |
Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also mediates monomethylation of 'Lys-56' of histone H3 (H3K56me1) in G1 phase, leading to promote interaction between histone H3 and PCNA and regulating DNA replication. Also weakly methylates 'Lys-27' of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltransferase activity is not required for DNA methylation, suggesting that these 2 activities function independently. Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. May also methylate histone H1. In addition to the histone methyltransferase activity, also methylates non-histone proteins: mediates dimethylation of 'Lys-373' of p53/TP53. Also methylates CDYL, WIZ, ACIN1, DNMT1, HDAC1, ERCC6, KLF12 and itself.
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ET7110-08·Anti-G9a Antibody
¥1500 - 2500








