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文献和实验Herpes Simplex Virus 1 (HSV-1)-Based Vectors
Herpes simplex virus type 1 (HSV-1) is a neurotropic virus displaying several outstanding adaptations to the nervous system, and each of them can be rationally exploited in the design of gene therapy vectors with regard to neurological
Gene therapy is defined as the alteration of the genetic material of a cell with resultant benefit to a patient. Gene transfer has two broad categories: one in which a therapeutic gene is delivered to the cells with the aim of treating a disease
Oncolytic Herpes Simplex Virus Engineering and Preparation
Herpes simplex virus-1 (HSV-1) is an enveloped, double-stranded DNA virus that has been used with modification as an oncolytic virus against a number of tumor types. Modifications that make HSV-1 replication-�conditional, i.e., selectively
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