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文献和实验ANTIBODY BINDING TO PROTEIN A AND PROTEIN G
of various immunoglobulines. Protein A is a 42 kDa polypeptide that binds the residues in the CH2 and CH3 domains of immunoglobulin heavy chains. Protein G is an approximatley 30 kDa polypeptide that binds immunoglobulins and albumin. Recombinant protein G
G Protein-Coupled Receptors Disrupted in Human Genetic Disease
occurring GPCR mutations. Various degrees of inactive, overactive, or constitutively active receptors have been identified. These mutations often alter ligand binding, G protein coupling, receptor desensitization, and receptor recycling. The role
Receptor Databases and Computational Websites for Ligand Binding
interactions. A number of websites in the public domain provide useful data-mining tools and contain information on specific families of receptors or receptor subfamilies, such as the G protein-coupled receptors (GPCRs) (1 , 2 ), nuclear receptors, ion
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