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文献和实验AntibodyCytotoxic Agent Conjugates: Preparation and Characterization
cytotoxic agents that inhibit essential cellular targets such as microtubules or DNA. Antibody–cytotoxic agent conjugates (ACCs) against several types of cancer are currently in advanced stages of clinical trials and one, gemtuzumab ozogamicin (Mylotarg�
Anti-GFP/BrdU In Situ Immunostaining
IgG (Jackson ImmunoResearch, 111-096-006) Biotinylated anti-BrdU (AbCam, ab2284-125) Streptavidin-Alexa Flour 555 (Invitrogen/Molecular Probes, S21381) Goat serum Horse serum BSA 2N HCl DAPI Fluorescent mounting medium (Vectashield
The Design, Production, and Validation of an Anti-HIV Type 1 Ribozyme
The development of acquired immunodeficiency syndrome (AIDS) generally takes of the order of ten years with no effective therapy currently available (1 ,2 ). HIV, the causative agent, exhibits tropism for CD4+ T-lymphocytes, the primary
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