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- 2025年06月25日
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文献和实验Purification and Characterization of Human and Mouse Complement C3
Complement component C3 is the most abundant complement protein in plasma, central to all three complement activation pathways and essential to complement amplification. Thus, it is one of the most extensively studied complement proteins
Purification of Human Complement Protein C5
Complement C5 is cleaved by proteolysis in the terminal phase of complement activation generating the pro-inflammatory C5a and membrane attack complex nucleator C5b. Whereas purification of its paralogues C3 and C4 from plasma is relatively
Complement Deposition in Tissues
The human complement (C) system is composed of about 20 components in blood plasma (Chapter 1 ). Of these, many become deposited at sites of complement attack and are detected by immunohistochemical methods. C3b, C4b, and their fragments remain
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