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文献和实验Conventional Cytogenetics in Myeloma
Chromosome analysis has become an important diagnostic tool in the assessment of patients with multiple myeloma. Conventional cytogenetic analysis of myeloma cells is complicated by the difficulty in inducing myeloma cells to divide. A method
The severe combined immune deficient human (SCID-hu) myeloma model is the only available model in which primary myeloma cells grow in vivo in a human bone marrow microenvironment. A SCID mouse receives an implanted human fetal bone
Multiple Myeloma: Challenges and Opportunities
Multiple myeloma (MM) is a B-cell neoplasm in which malignant plasma cells accumulate in the bone marrow and produce lytic bone lesions and excessive amounts of a monoclonal protein (usually an immunoglobulin of the IgG or IgA type or free
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