ABBIOTEC特约代理商|250505 Glucosylc

Development of a Mammalian Tet-On Expression Cell Line: Glucosylceramide Synthase Regulates TNF--Induced Apoptosis

by TNF-α (14 ). Glucosylceramide synthase (GCS), converting ceramide into glucosylceramide (15 ), exerts strong influence over cellular ceramide levels and is thus a major modulator of programmed cell death (16 ). Introducing the GCS gene into TNF

Gene Therapy in Cancer Via Use of a Retrovector Having a Tumor Specificity and Expressing Inducible Nitric Oxide Synthase

for tumor-specific targeting by retrovectors. The conventional suicidal gene delivery systems need additional drugs other than their gene products. The inducible nitric oxide synthase (iNOS) gene product yields nitric oxide (NO), which directly induces

A fluorescence microscopy method for quantifying the detection of prostaglandin endoperoxide H synthase-1 and CD-41 in MEG-01 cells

the immortalized human megakaryoblastic cell line MEG-01, which can be induced to differentiate into platelet-like structures upon addition of TPA as a model system to study PGHS-1 gene expression. Using a specific antibody to PGHS-1 we have developed a technique