Anti-IRF4 Polyclonal Antibody

产品简介

英文名称	Anti-IRF4 Polyclonal Antibody
宿主	Rabbit
别名	interferon regulatory factor 4； IRF 4； IRF4； LSIRF； Multiple myeloma oncogene 1； MUM1； NF EM5
稀释比例	WB 1:1000-1:3000. IHC 1:50-200.
蛋白分子量	52kDa
Gene ID	3662
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human IRF4
亚细胞定位	Cytoplasm Nucleus
Swiss Prot	Q15306
背景资料	The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.
Public Immunogen Range	1-451aa
克隆类型	Polyclonal Antibody
交叉反应	Human Mouse
应用	WB IHC
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图

Western blot analysis with IRF4 antibody diluted at 1:2000;Lane: Raji,A431,Mouse lung,Mouse spleen

Immunohistochemistry of paraffin-embedded Human colorectal cancer with IRF4 antibody diluted at 1:100

Immunohistochemistry of paraffin-embedded Human stomach cancer with IRF4 antibody diluted at 1:100