- ￥960 - 1600
- Solarbio
- 北京
- K107109P
- 2025年07月15日
- WB
- Rabbit
- Human Mouse Rat
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
IgG
- 形态：
液体
- 保存条件：
Store at -20°C. Avoid freeze / thaw cycles.
- 克隆性：
Polyclonal Antibody
- 标记物：
Nucleus Cytoplasm
- 适应物种：
Human Mouse Rat
- 保质期：
现询客服
- 抗原来源：
现询客服
- 库存：
99
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
WB
- 浓度：
现询客服
- 靶点：
STRAP
- 抗体名：
MAP activator with WD repeats;MAWD;PT WD;STRAP;UNR interacting protein;UNRIP;WD 40 repeat protein PT WD
- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | ￥960.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 英文名称 | Anti-STRAP Polyclonal Antibody |
| 宿主 | Rabbit |
| 别名 | MAP activator with WD repeats;MAWD;PT WD;STRAP;UNR interacting protein;UNRIP;WD 40 repeat protein PT WD |
| 稀释比例 | WB 1:5000-8000. |
| 蛋白分子量 | 40kDa |
| Gene ID | 11171 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human STRAP |
| 亚细胞定位 | Nucleus?Cytoplasm |
| Swiss Prot | Q9Y3F4 |
| 背景资料 | Unrip is part of the SMN complex that plays a role in snRNP assembly in the cytoplasm and pre mRNA splicing in the nucleus. Unrip interacts directly with Gemin 6 and Gemin 7 in the SMN complex. It is associated with the complex in the cytoplasm but not in the nucleus and thus is thought to play a role in it's subcellular localisation. It is a ubiquitously expressed protein that acts as an inhibitor of TGF-beta signaling and an important regulator of cell proliferation. Stable expression of STRAP results in activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway and in down-regulation of the cyclin-dependent kinase inhibitor p21 (Cip1), which results in retinoblastoma protein hyperphosphorylation. Upregulation of STRAP might play a role in tumor development as an early event for colorectal cancers. It is the first component of the U snRNP assembly machinery that associates with SMN complex in a compartment-specific way and plays a crucial role in the intracellular distribution of SMN1. |
| Public Immunogen Range | 1-350aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human Rat Mouse |
| 应用 | WB |
| 规格 | 50ul 100ul |
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图
Western blot analysis with STRAP antibody diluted at 1:6000;Lane:HeLa,293T,HepG2,Jurkat
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文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
a simple ELISA method to detect human anti-antibody response.
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