Anti-RNF146 Polyclonal Antibod

产品简介

英文名称	Anti-RNF146 Polyclonal Antibody
宿主	Rabbit
别名	dactylidin;dJ351K20.1;DKFZp434O1427
稀释比例	IHC 1:50-200.
蛋白分子量	39kDa
Gene ID	81847
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human RNF146
亚细胞定位	Nucleus?Cytoplasm
Swiss Prot	Q9NTX7
背景资料	The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF146 (RING finger protein 146), also known as Dactylidin, is a 359 amino acid protein that contains one RING-type zinc finger and one WWE domain. Via its RING-type zinc finger, RNF146 may play a role in transcriptional regulation and protein degradation events. Defects in the gene encoding RNF146 are associated with Alzheimer's disease (AD) and may lead to a higher risk of breast cancer. Two isoforms of RNF146 exist due to alternative splicing events.
Public Immunogen Range	1-359aa
克隆类型	Polyclonal Antibody
交叉反应	Human
应用	IHC
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图

Immunohistochemistry?of?paraffin-embedded?Human Cervical cancer?with?RNF146 antibody diluted at 1:100