手机验证
KLH conjugated synthetic peptide derived from human CDK4
IgG
冻干粉
Store at -20°C. Avoid freeze / thaw cycles.
单克隆
Cell membrane Cytoplasm Nucleus
Human Mouse Rat Pig Cow
现询
KLH conjugated synthetic peptide derived from human CDK4
K009494P
详询
999
北京索莱宝科技有限公司
Rabbit
WB ELISA IHC-P IHC-F Flow-Cyt IF
WB 1:500-2000. ELISA 1:500-1000. IHC-P 1:100-500. IHC-F 1:100-500. Flow-Cyt 1μg/Test. IF 1:100-500.
CDK4
Anti-CDK4 Polyclonal Antibody
Cdk 4;CDK4 protein;Cell division kinase 4;Cell division protein kinase 4;CMM 3;CMM3;Crk3;Cyclin dependent kinase 4;Melanoma cutaneous malignant 3;MGC14458;p34 cdk4;PSK J3;CDK4_HUMAN
50ul/100ul
规格: | 50ul | 产品价格: | ¥2000.0 |
---|---|---|---|
规格: | 100ul | 产品价格: | ¥3500.0 |
英文名称
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Anti-CDK4 Polyclonal Antibody
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中文名称
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周期蛋白-依赖性蛋白激酶4抗体
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靶标
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CDK4
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别名
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Cdk 4;CDK4 protein;Cell division kinase 4;Cell division protein kinase 4;CMM 3;CMM3;Crk3;Cyclin dependent kinase 4;Melanoma cutaneous malignant 3;MGC14458;p34 cdk4;PSK J3;CDK4_HUMAN
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背景资料
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Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the sub*sequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also phosphorylates SMAD3 in a cell-cycle-dependent manner and represses its transcriptional activity. Component of the ternary complex, cyclin D/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.
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Swiss Prot
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P11802
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Gene ID
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1019
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亚细胞定位
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Cell membrane Cytoplasm Nucleus
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宿主
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Rabbit
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克隆类型
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Polyclonal Antibody
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亚型
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IgG
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交叉反应
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Rat ; Mouse ; Human
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预测交叉反应
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Pig;Cow
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蛋白分子量
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34kDa
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应用
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ELISA ; FCM ; IF ; ICC ; IHC ; WB
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稀释比例
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WB 1:500-2000. ELISA 1:5000-10000. IHC 1:100-500. FCM 1μg/Test. ICC 1:100. IF 1:100-500.
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免疫原
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A synthetic peptide of human CDK4
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Public Immunogen Range
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241-303/303aa
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纯化方法
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Affinity purification
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储存液
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Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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保存
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Store at -20℃. Avoid freeze / thaw cycles.
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规格
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50ul ; 100ul
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单位
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支
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These protocols are for reference only. Solarbio does not independently validate these methods.
Quick spin before use. If you have any questions, please contact us.
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