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Anti-Amyloid, beta 1-40/42; 50

μL
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  • 询价
  • AB5076
  • 2025年07月14日
  • ELISA;Western Blotting
  • Rabbit
  • Human;Mouse
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默克生命科学
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 应用范围：

      ELISA;Western Blotting

    • 宿主：

      Rabbit

    • 库存：

      大量

    • 抗原来源：

      0

    • 适应物种：

      Human;Mouse

    • 是否单克隆：

      2

    • 规格：

      50 μL

    Species Reactivity Key Applications Host Format Antibody Type
    H, M ELISA, IH, WB Rabbit Serum Polyclonal Antibody
    Description:
    Anti-Amyloid, β 1-40/42
    Replaces:
    AB5408
    Specificity:
    Recognizes beta-amyloid 1-40/42. One of the most important and initial steps which causes loss of memory and cognition in Alzheimer's Disease (AD) involves proteolytic cleavage of amyloid precursor protein (APP, chromosome 21) releasing short 40, 42 & 43 amino acid peptides (beta amyloid 1-40, 1-42 and 1-43). Polymerization of beta-amyloid and subsequent neuronal deposit (amyloid) leads to the degeneration of neurons involved in memory and cognition. The immunogen peptide shows homology with beta-amyloid 1-28 and beta-amyloid 12-28. No cross reactivity is observed with CGRP.
    Key Applications:
    • ELISA
    • Immunohistochemistry
    • Western Blotting
    Application Notes:
    Western blot: 1:1,000-1:5,000 (Chemiluminescence technique)

    Immunohistochemistry: 1:100 using formalin or paraformaldehyde fixed Alzheimer's brain tissue.

    ELISA: 1:10,000-1:100,000 (50-100 ng immunogen peptide /well).

    Immunoge control peptide is Catalog number AG365.

    Optimal working dilutions must be determined by the end user.
    Species Reactivity:
    • Human
    • Mouse
    Immunogen:
    A synthetic beta-amyloid peptide 1-40 conjugated to BSA.
    Control:
    Alzheimer's disease brain tissue, whole tissue extracts from mouse brain
    Presentation:
    Rabbit Serum. Liquid and 0.1% sodium azide.
    Storage Conditions:
    Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
    Gene Symbol:
    • APP
    • PN-II
    • AD1
    • ABETA
    • CTFgamma
    • APPI
    • ABPP
    • A4
    • CVAP
    • PN2
    • PreA4
    • AAA
    Antibody Category:
    Neuroscience
    Antibody Sub-Category:
    Neurodegenerative Diseases
    Usage Statement:
    Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    Trade Name:
    Chemicon (Millipore)
    Format:
    Serum
    Host:
    Rabbit
    Concentration:
    Variable
    Antibody Type:
    Polyclonal Antibody

    更多产品技术资讯，请访问密理博中国博客：http://blog.milliporechina.com

    A synthetic beta-amyloid peptide 1-40 conjugated to BSA. 详细描述见链接：http://www.millipore.com/catalogue/item/AB5076

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    图标文献和实验
    相关实验

    • FA Extraction of [insoluble] Amyloid beta from Mouse Brain

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    • Beta-gal Assay

      Beta-gal Assay Adapted from Current Protocols in Molecular Biology 1. Grow 5ml YEPD cultures to mid-log phase. 2. Centrifuge and resuspend cells in 5ml Z-buffer, then place on ice. 3. Measure OD600. 4. Use straight

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