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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
CDK-IN-2
- 库存:
10
- 供应商:
TargetMol
- CAS号:
1269815-17-9
- 规格:
25 mg/10 mg/500 mg/50 mg/1 mL/5 mg/1 mg/100 mg/2 mg
| 规格: | 25 mg | 产品价格: | ¥2570.0 |
|---|---|---|---|
| 规格: | 10 mg | 产品价格: | ¥1510.0 |
| 规格: | 500 mg | 产品价格: | ¥9870.0 |
| 规格: | 50 mg | 产品价格: | ¥3670.0 |
| 规格: | 1 mL | 产品价格: | ¥987.0 |
| 规格: | 5 mg | 产品价格: | ¥948.0 |
| 规格: | 1 mg | 产品价格: | ¥352.0 |
| 规格: | 100 mg | 产品价格: | ¥4970.0 |
| 规格: | 2 mg | 产品价格: | ¥517.0 |
Product Introduction
Bioactivity
英文名:CDK-IN-2
描述:CDK-IN-2 (CDK inhibitor II) is a potent and specific CDK9 inhibitor (IC50: <8 nM).

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文献和实验A uniform procedure for the purification of CDK7/CycH/MAT1, CDK8/CycC and CDK9/CycT1
We have established a uniform procedure for the expression and purification of the cyclin-dependent kinases CDK7/CycH/MAT1, CDK8/CycC and CDK9/CycT1. We attach a His6 -tag to one of the subunits of each complex and then co-express
CDK-Activating Kinases: Detection and Activity Measurements
for this activating phosphorylation, the CDK-activating kinase (CAK), is therefore essential for proliferation of all eukaryotic cells. We describe methods to assess the T-loop phosphorylation state of the major mammalian CDKs in vivo; to measure the levels of CAK
Functional Analysis of CDK Inhibitor p21WAF1
p21WAF1 was originally identified as a protein that binds and inhibits cyclin-dependent kinases (CDKs). p21WAF1 is recognized to have at least two separate roles—first as a CDK inhibitor, and second as an inhibitor of PCNA, an accessory
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