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- TargetMol
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- 2025年07月15日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
Saquinavir mesylate
- 库存：
10
- 供应商：
TargetMol
- CAS号：
149845-06-7
- 规格：
10 mg
Product Introduction
Bioactivity
英文名:Saquinavir mesylate
描述:Saquinavir mesylate (Ro 31-8959/003) is an Inhibitor of HIV Proteaseused in antiretroviral therapy
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文献和实验Detection of BCR-ABL Mutations and Resistance to Imatinib Mesylate
The major mechanism of imatinib resistance for patients with chronic myeloid leukemia (CML) is clonal expansion of leukemic cells with mutations in the Bcr-Abl fusion tyrosine kinase that reduce the capacity of imatinib to inhibit kinase
-4 and C-5 centers ( 3 ). After formatron of the mesylate, from the recycled material the amine function is introduced through azrde displacement of the mesylate, followed by reduction ( 4 ) and protectron with the t -BOC group. Finally, the lactone
Identifying and Characterizing HIV Protease Inhibitors
have been designed and synthesized since, in fact, four protease inhibitors—saquinavir (Ro-31,8959), ritonavir (ABT-538), indinavir (L-735,524), and Nelfinavir (AG1343)—are effective in clinical trials to treat HIV disease (4 –6 ) and recently were approved
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