- ￥578 - 6890
- TargetMol
- 美国
- T7677
- 2025年07月14日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
JNK Inhibitor VIII
- 库存：
10
- 供应商：
TargetMol
- CAS号：
894804-07-0
- 规格：
100 mg/50 mg/25 mg/5 mg/1 mg/10 mg/1 mL
| 规格： | 100 mg | 产品价格： | ￥6890.0 |
|---|---|---|---|
| 规格： | 50 mg | 产品价格： | ￥4900.0 |
| 规格： | 25 mg | 产品价格： | ￥3480.0 |
| 规格： | 5 mg | 产品价格： | ￥1230.0 |
| 规格： | 1 mg | 产品价格： | ￥578.0 |
| 规格： | 10 mg | 产品价格： | ￥1920.0 |
| 规格： | 1 mL | 产品价格： | ￥1370.0 |
Product Introduction
Bioactivity
英文名:JNK Inhibitor VIII
描述:JNK Inhibitor VIII (TCS JNK 6o) is an ATP-competitive selective inhibitor of c-Jun N-terminal kinase (JNK)(IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively).
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文献和实验dream_reloaded A potent, cell-permeable, selective, and reversible inhibitor of c-Jun N-terminal kinase (JNK) (IC50 = 40 nM for JNK-1 and JNK-2 and 90 nM for JNK-3). The inhibition is competitive with respect to ATP. Exhibits over 300-fold
Nijmegen-Bethesda Assay to Measure Factor VIII Inhibitors
Hemophilia A is an inherited bleeding disorder caused by a deficiency of factor VIII coagulant activity (FVIII:C). Patients are treated with infusions of either plasma-derived or recombinant factor VIII. However, some patients develop
. Similar biphasic pattern of JNK activation is also observed in the parental PC12 cells. Using the specific JNK inhibitor SP600125, we show that the biphasic activation is necessary for neurite outgrowth and branching, and that inhibition
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