- ￥1890 - 17500
- TargetMol
- 美国
- T15584
- 2025年07月16日
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- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
Integrin Antagonists 27
- 库存：
10
- 供应商：
TargetMol
- CAS号：
593274-97-6
- 规格：
100 mg/1 mL/2 mg/50 mg/25 mg/5 mg
| 规格： | 100 mg | 产品价格： | ￥17500.0 |
|---|---|---|---|
| 规格： | 1 mL | 产品价格： | ￥2830.0 |
| 规格： | 2 mg | 产品价格： | ￥1890.0 |
| 规格： | 50 mg | 产品价格： | ￥12500.0 |
| 规格： | 25 mg | 产品价格： | ￥9620.0 |
| 规格： | 5 mg | 产品价格： | ￥2890.0 |
Product Introduction
Bioactivity
英文名:Integrin Antagonists 27
描述:Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist. It has a binding affinity of 18 nM and as a novel anticancer agent.
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文献和实验Cell-Free Ligand-Binding Assays for Integrin LFA-1
Integrin LFA-1 plays an important role in leukocyte trafficking to inflammatory sites as well as the interaction of T cells with antigen-presenting cells. Inhibition of the LFA-1:ICAM-1 interactions is a promising therapeutic approach
-induced responses, including a down-regulation of the cyclin-dependent kinase (Cdk2) inhibitors p21CIP1 and p27KIP1 , while attachment to P-L-L did not. We conclude that engagement of the FN-receptor integrin α5β1 induces integrin signaling regulating
Solid Phase Assays for Studying ECM ProteinProtein Interactions
is detected by addition of an avidin–peroxidase conjugate followed by a colorimetric detection step. This type of assay is particularly well suited for studying the interaction of ECM proteins with integrins. The screening of antagonists of integrin–ligand
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