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Anti-phospho-CrkL (Tyr207)

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  • 询价
  • 09-466
  • 2025年07月09日
  • Western Blotting
  • Rabbit
  • Human;Rat;Mouse
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 应用范围：

      Western Blotting

    • 宿主：

      Rabbit

    • 抗原来源：

      0

    • 适应物种：

      Human;Rat;Mouse

    • 库存：

      大量

    • 是否单克隆：

      2

    • 规格：

      100 μL

    Product Images

    Western Blot Analysis:
    K562 cell lysate was resolved by SDS-PAGE, transferred to PVDF, and probed with anti-phospho-CrkL (Tyr207) (1:1,000). Pro...

    Western Blot Analysis-Peptide Blocking:
    K562 cell lysate was resolved by SDS-PAGE, transferred to PVDF, and probed with anti-phospho-CrkL (Tyr207...
    Species Reactivity Key Applications Host Format Antibody Type
    H, R, M WB Rabbit Affinity Purified Polyclonal Antibody
    Description:
    Anti-phospho-CrkL (Tyr207)
    Background Information:
    CRKL belongs to a family of adaptor proteins containing SH2/SH3 domains that couple to effector proteins including p130CAS, SOS, Abl, and Arg. CRKL plays a role in the mediation of Integrin- and Rac-dependent cell migration and in Ras-dependent activation of JNK. The protein is also involved in T-cell activation. Phosphorylation of CrkL on Tyr207 is known to be correlated with its inhibition.
    Specificity:
    Recognizes CrkL only when phosphorylated on Tyr207.
    Key Applications:
    Western Blotting
    Species Reactivity:
    • Human
    • Rat
    • Mouse
    Immunogen:
    KLH synthetic peptide including and encompassing Tyr 207 of human CrkL.
    Modifications:
    Phosphorylation
    Molecular Weight:
    39 kDa
    Control:
    K562
    Presentation:
    Purified rabbit polyclonal IgG in storage buffer containing PBS with 0.05% sodium azide in 50% glycerol.
    Storage Conditions:
    Stable for 1 year at 2-8°C from date of receipt.
    Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
    Gene Symbol:
    • v-crk avian sarcoma virus CT10 oncogene homolog-like
    • v-crk sarcoma virus CT10 oncogene homolog (avian)-like
    • Crk Like
    Quality Assurance:
    Routinely evaluated by western blot on K563 cell lysates.
    Antibody Category:
    Signaling
    Antibody Sub-Category:
    Cytoskeletal Signaling
    Usage Statement:
    Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    Trade Name:
    Upstate (Millipore)
    Format:
    Affinity Purified
    Host:
    Rabbit
    Antibody Type:
    Polyclonal Antibody

    更多产品技术资讯，请访问密理博中国博客：http://blog.milliporechina.com

    KLH synthetic peptide including and encompassing Tyr 207 of human CrkL. 详细描述见链接：http://www.millipore.com/catalogue/item/09-466

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