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- 2025年11月06日
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文献和实验Calculating HIV-1 Infectious Titre Using a Virtual TCID50 Method
supernatants or patient samples is the tissue culture dose for 50% infectivity (TCID50 ), which provides an accurate assessment of the level of infectious HIV-1. However, it is a time-consuming technique which typically takes two or more weeks to complete
=0.869Pn=0.135P=0.869+0.849+0.616+0.391+0.282+0.135=3.142Xm=lg100=2lgI=lg100/50=0.301lgIC50=2-0.301*(3.142-(3-0.869-0.135)/4)=1.655IC50=45.186该药物的IC50值为 45.186ug/ml最近做一个药物抗呼吸道合胞病毒的药效学试验，看大多数文献里，病毒滴定中的TCID50、药物毒性试验中的半数中毒浓度（TC50）最大无毒浓度（TC0）以及药物半数有效浓度（EC
dilution of antibody. However, it has the important advantage of directly measuring the effect of antibody on virus median tissue culture infectious dose (TCID50 ). In addition, the IRA is unaffected by variation in virus growth kinetics
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