Xanomeline (oxalate)

一种强效的毒蕈碱型乙酰胆碱受体激动剂（对M1、M2、M3、M4和M5受体的EC50值分别为0.3、92.5、5、52和42纳摩尔）；在大鼠和卷尾猴中具有抗精神病样活性；增强记忆功能，对治疗阿尔茨海默病有潜在的应用价值。A potent agonist of muscarinic acetylcholine receptors (EC50 values are 0.3, 92.5, 5, 52, and 42 nM for M1, M2, M3, M4, and M5, respectively); has antipsychotic-like activities in rats and Cebus monkeys; enhances memory function and has utility in treating Alzheimer's Disease.