AL 34662

一种具有降眼压活性的强效5-HT2受体激动剂；与人类和大鼠大脑皮层匀浆中的5-HT2受体结合，IC50值分别为1.5和0.77nM；给药后六小时，剂量为100µg时眼压降低25%，剂量为300µg时眼压降低33%A potent 5-HT2 receptor agonist with ocular hypotensive activity; binds to the human and rat 5-HT2 receptors in cerebral cortex homogenates with IC50 values of 1.5 and 0.77 nM, respectively; lowers IOP 25 % at a dose of 100 µg and 33 % at 300 µg at six hours post dose.