ATF2 (Phospho-Ser490,498) Poly

抗原：与人类ATF2磷酸化Ser490,498周围氨基酸残基相对应的合成磷酸肽；宿主：兔；交叉反应性：(+)人类ATF2；预计与大鼠ATF2发生反应；应用：WB和IHC（冷冻切片）；ATF2与AP-1和CREDNA反应元件结合，是ATF/CREB亮氨酸拉链蛋白家族的成员。它参与了许多基因的转录调控，包括细胞因子、细胞周期控制和细胞凋亡。Antigen: synthetic phosphopeptide corresponding to amino acid residues surrounding phospho-Ser490,498 of human ATF2; Host: rabbit; Cross-reactivity: (+) human ATF2; expected to react with rat ATF2; Applications: WB and IHC (frozen sections); ATF2 binds to both AP-1 and CRE DNA response elements and is a member of the ATF/CREB family of leucine zipper proteins. It has been implicated in the transcriptional regulation of a number of genes including cytokines, cell cycle control, and apoptosis.