S1P3 Polyclonal Antibody

抗原：人类S1P3氨基酸12-25；宿主：兔；交叉反应性：(+)人类、小鼠、大鼠S1P3；应用：ICC和WB。S1P3是被S1P激活的五种GPCR之一，耦合Gi/o-ERK、Gq-PLC和G12/13-Rho通路以介导S1P诱导的细胞增殖、生存、迁移及相关信号事件。S1P3在多种组织中广泛表达，表明该受体具有多样的生理功能。Antigen: Human S1P3 amino acids 12-25; Host: Rabbit; Cross Reactivity: (+) Human, mouse, and rat S1P3; Application(s): ICC and WB; S1P3 is one of five GPCRs that are activated by S1P. It couples to Gi/o-ERK, Gq-PLC, and G12/13-Rho axes to mediate S1P-induced cell proliferation, survival, migration, and related signaling events. S1P3 is widely expressed in various tissues, suggesting diverse physiological functions of this receptor.