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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
IgG
- 亚型:
Affinity purification
- 形态:
液体
- 保存条件:
Store at -20°C. Avoid freeze / thaw cycles.
- 克隆性:
单克隆
- 适应物种:
Human Mouse Rat
- 目录编号:
3125
- 库存:
999
- 供应商:
北京索莱宝科技有限公司
- 宿主:
Rabbit
- 应用范围:
WB IHC
- 靶点:
HLA-DRB3
- 抗体英文名:
Anti-HLA-DRB3 Polyclonal Antibody
- 抗体名:
HLA-DRB3
- 规格:
50ml/100ml
| 规格: | 50ml | 产品价格: | ¥960.0 |
|---|---|---|---|
| 规格: | 100ml | 产品价格: | ¥1600.0 |
| 英文名称 | Anti-HLA-DRB3 Polyclonal Antibody |
| 宿主 | Rabbit |
| 别名 | HLA-DRB3;HLA-DR1B;HLA-DR3B;major histocompatibility complex;class II;DR beta 3 |
| 稀释比例 | WB 1:1000-3000. IHC1:100-300. |
| 蛋白分子量 | 30kDa |
| Gene ID | 3125 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human HLA-DRB3 |
| 亚细胞定位 | Cell membrane Cytoplasm |
| Swiss Prot | P79483 |
| 背景资料 | HLA-DRB3 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. The presence of DRB3 is linked with allelic variants of DRB1, otherwise it is omitted. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9. |
| Public Immunogen Range | 1-266aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human Rat Mouse |
| 应用 | WB IHC |
| 规格 | 50ul 100ul |
备注:
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
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文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇:make an Antibody against a Peptides 下一篇:Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
a simple ELISA method to detect human anti-antibody response.
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