Anti-SPIN2B Polyclonal Antibod

产品简介

英文名称	Anti-SPIN2B Polyclonal Antibody
宿主	Rabbit
别名	SPIN2B;SPIN-2;SPIN-2B;SPIN2_duplicate;TDRD26;dJ323P24.2;spindlin-2B
稀释比例	IHC 1:50-200.
蛋白分子量	29kDa
Gene ID	474343
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human SPIN2B
亚细胞定位	Nucleus Cytoplasm
Swiss Prot	Q9BPZ2
背景资料	Human SPIN2 expressed by 2 IL3-dependent murine myeloid cell lines was moderately antiapoptotic following IL3 removal, but it was unable to block apoptosis induced by the chemotherapy agent doxorubicin. On the contrary, SPIN2-expressing cells were more sensitive to doxorubicin-mediated cell death. Also, SPIN2 did not combat the proapoptotic effects of Fas ligand stimulation in the Jurkat human T-cell line. Deletion of the C-terminal amino acids of SPIN2 diminished its antiapoptotic activity. In the murine myeloid cells, SPIN2 overexpression increased the cell number doubling times and slowed their rate of growth. There was also an increased percentage of cells in G2/M, which was more pronounced following IL3 withdrawal.
Public Immunogen Range	1-259aa
克隆类型	Polyclonal Antibody
交叉反应	Human Rat Mouse
应用	IHC
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图