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- CN1005
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- 2025年07月11日
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- 详细信息
- 文献和实验
- 技术资料
- 抗体英文名：
Glutathione Antibody
- 宿主：
其它
- 供应商：
上海研卉生物科技有限公司
- 库存：
大量
- 抗原来源：
其它
- 是否单克隆：
0
- 规格：
100µg
Glutathione Antibody 的详细介绍
- 类 型：Tag抗体
Product Description: This antibody was developed using Glutathione (GSH)-KLH conjugates and affinity purified with antigen-specific affinity chromatography. The antibody could be utilized for detection and quantitation of the reduced (GSH) and oxidized (GSSG) glutathione, glutathionylated proteins and peptides.Catalog Number Pack Size Price(CNY) CN1005 100 µg ￥2000.00
Speciece: Rabbit
Formulation: 250 µg/mL in PBS with 50% Glycerol.
Storage & Stability: Store product at –20 ℃. Three years from date of shipping.
Immunogen: Glutathione-KLH conjugates linked through –S- bond.
Purification: Antigen-specific affinity chromatography.
Specificity: Pan-specific antibodies recognized both GSH and GSSG, glutathionylated proteins and peptides.
Applications: Quantitative ELISA, WB, IP (affinity chromatography), IF. IHC.
Scientific Description: Glutathione is a tripeptide. It contains an unusual peptide linkage between the amine group of cysteine and the carboxyl group of the glutamate side chain. Glutathione, an antioxidant, protects cells from toxins such as free radicals. Glutathione could also modified proteins via the cysteine residues and formed the glutationylated proteins via disulfide bind with the protein cysteine residue. Redox proteomics of glutathionylated proteins in oxidatively stressed human T lymphocytes have been reported.
Reference: 1.Maddalena Fratelli et al., 2001. PNAS,99: 3510.
2.Chen, YR. et al. 2007.Biol Chem. 282(45):32640-54.
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文献和实验C10 H17 N3 SO6 。为γ -L-谷氨酰 -L-半胱氨酞甘氨酸（ 1）。谷胱甘肽如（ 2）所示在活体内参与氧化还原反应。所以具有保护如组织蛋白酶、番木瓜酶及琥珀酸脱氢酶那样具有 SH基酶的 SH基作用。另外是催化甲基乙二醛形成乳酸的乳酰谷胱甘肽裂解酶（ EC． 4． 4． 1． 5）不可缺少的辅助基质。在解毒作用中形成硫醚氨酸，被认为有毒物质先与谷胱甘肽结合使谷氨酸与甘氨酸部分切断。
Reduced Glutathione and Glutathione Disulfide
Glutathione (GSH; L- -glutamyl-L-cysteinl-glycine) plays an important role in the prevention of radical mediated injury to the body. It does so as a radical scavenger and by supplying GSH to the antioxidant enzymes described in Chapter 29
Measurement of Malondialdehyde, Glutathione, and Glutathione Peroxidase in SLE Patients
damage include malondialdehyde (MDA), antioxidant scavengers as glutathione (GSH), and glutathione peroxidase (GSH Px), which all correlate well with SLE disease activity. Amelioration of some clinical manifestations of SLE may be expected by targeting
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