【rmS100b】重组猕猴S100钙粘合蛋白B/【rmS10

产品名称：【rmS100b】重组猕猴S100钙粘合蛋白B-Recombinant Rhesus Macaque S100 Calcium Binding Protein B

产品货号：PRO-1236

产品规格：1mg///20ug///5ug

来源宿主：大肠杆菌中重组表达

保存建议：【rmS100b】重组猕猴S100钙粘合蛋白B-Recombinant Rhesus Macaque S100 Calcium Binding Protein B重组猕猴S100钙粘合蛋白B产品在室温保存3周，于-18°C以下长期保存.一旦溶解，于4°C保存2-7天.避免反复冻融

背景资料：S100b is a member of the S100 family of proteins which are a family of EF-hand calcium binding proteins that exist mostly as dimers of the 20 currently identified individual S100 monomers. The S100B homodimer is expressed in cells of the central nervous system， glial cells and in certain peripheral cells e.g. Schwann cells， melanocytes， adipocytes and chondrocytes. S100 proteins are localized either in the cytoplasm or the nucleus of a wide range of cells. S100 proteins are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. There are at least 13 members in the S100 gene family， which are located as a cluster on chromosome 1q21； however， S100b is located at 21q22.3. The determination of S100B in serum levels may be used to monitor the extent of brain injury and malignant melanoma. S100b proteins may have a role in Neurite extension， proliferation of melanoma cells， stimulation of Ca2+ fluxes， inhibition of PKC-mediated phosphorylation， astrocytosis and axonal proliferation， and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of the S100b gene are implicated in several neurological， neoplastic， and other types of diseases， including Alzheimer’s disease， Down’s syndrome， epilepsy， amyotrophic lateral sclerosis， melanoma， and type I diabetes.

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以色列ProSpec-Tany公司专注于细菌来源重组蛋白质生产。其独有细菌和哺乳动物表达和蛋白折叠技术使其成为闻名中外科研级蛋白供应商。ProSpec-Tany是海内上能提供蛋白种类很多公司之一。领先生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。作为多家知名品牌代理，艾美捷与ProSpec一起为研究者们提供优质、全新细胞生物学研究工具而不断扩大产品及服务质量。

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关键词：Recombinant Rhesus Macaque S100 Calcium Binding Protein B，【rmS100b】重组猕猴S100钙粘合蛋白B，S100b