胃蛋白酶/胃蛋白酶原活性测定试剂盒/胃蛋白酶/胃蛋白酶原活性

产品名称：胃蛋白酶/胃蛋白酶原活性测定试剂盒/胃蛋白酶/胃蛋白酶原活性测定试剂盒/胃蛋白酶/胃蛋白酶原活性测定试剂盒-Pepsin/Pepsinogen Activity Assay Kit /Pepsin/Pepsinogen Activity Assay Kit /Pepsin/Pepsinogen Activity Assay Kit

产品货号：K446-100

产品规格：100assays

背景资料：待更新

保存建议：胃蛋白酶/胃蛋白酶原活性测定试剂盒/胃蛋白酶/胃蛋白酶原活性测定试剂盒/胃蛋白酶/胃蛋白酶原活性测定试剂盒-Pepsin/Pepsinogen Activity Assay Kit /Pepsin/Pepsinogen Activity Assay Kit /Pepsin/Pepsinogen Activity Assay Kit -20°C

产品描述：Pepsin (EC 3.4.23.1) is a peptidase A1 family aspartic protease that serves as a primary digestive enzyme in the mammalian stomach. Pepsin is synthesized in the chief cells of the gastric mucosa as the inactive pro-enzyme pepsinogen, which contains a 44 amino acid autoinhibitory domain. The proenzyme is packaged into granules and stored inside the gastric mucosal cells. When food is consumed, neuronal signals traveling along the vagus nerve trigger secretion of HCl and pepsinogen into the stomach. In the highly acidic environment of the stomach, pepsinogen unfolds and undergoes autocatalytic cleavage, forming the active protease pepsin. Infection by the bacterium H. pylori induces hypersecretion of both stomach acid and pepsin, contributing to the formation of gastric and duodenal ulcers. In addition, excessive amounts of pepsin can play a role in the degradation of the esophageal and laryngeal tissue observed in chronic gastroesophageal reflux disease. While the majority of pepsinogen is expressed in the gastric mucosa, a small amount of the inactive enzyme is also released into the blood. Serum pepsinogen levels correlate with functional changes to gastric mucosa and are often measured for the screening of gastric cancer and chronic H. pylori-induced gastritis. BioVision’s Pepsin Assay Kit is a homogenous assay that allows for quantification of pepsin activity in gastric tissue and various biological fluids. The assay utilizes a synthetic peptide substrate bearing both a fluorophore and a fluorescence quencher. Upon cleavage by pepsin, the fluorophore-bearing peptide fragment is unquenched to produce a bright fluorescent signal (Ex/Em = 328/418 nm). Lysosomal aspartic proteases in the peptidase A1 family (Cathepsin D and E) do not interfere with the assay. The assay is rapid, simple to perform and is vastly more sensitive than the classical hemoglobin degradation assay, with a detection limit of 500 μU pepsin activity per well

点击：胃蛋白酶/胃蛋白酶原活性测定试剂盒/胃蛋白酶/胃蛋白酶原活性测定试剂盒/胃蛋白酶/胃蛋白酶原活性测定试剂盒-Pepsin/Pepsinogen Activity Assay Kit /Pepsin/Pepsinogen Activity Assay Kit /Pepsin/Pepsinogen Activity Assay Kit 查看更详细产品说明，更多应用、储存、价格、货期等信息请致电垂询BioVision中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看每日生物评论网站。

BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的领路人.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理，艾美捷与BioVision一起为研究者们提供最好、崭新的细胞生物学研究工具而不断扩大产品及服务质量.

艾美捷科技有限公司，通过提供完整的产品和服务体系、便利的客户关系和供应链管理，为生命科学研究工作者提供整体打包方案。我们的企业的核心价值观：“激情、敬业、学习、创新、合作、卓越”。激发我们内在的创造力，提供有竞争力的生物医学产品和服务，持续为客户创造最大价值是我们的企业使命。我们的企业愿景是成为受人尊重、世界知名的生物医学产品及服务供应商。艾美捷科技与国内外优秀的生物试剂供应商保持着密切的合作关系，目前已成为众多国际知名品牌的中国总代理或一级代理，主要包括：AmyJet、AAT Bioquest、Abnova、Agrisera、Biovision、Biosensis、Cayman Chemical、Caisson Labs、Cytoskeleton、CytoNiChe、Epigentek、Equitech-Bio、Hycult Biotech、Jackson、LifeSensors、ProSpec、Norgen Biotek、Mabtech、Matreya、iRegene、StressMarq、ImmunoReagents、SouthernBiotech、Origene、US Biological、Solis BioDyne等，可以在第一时间为用户提供最前沿的专业资讯、完备的产品及物流服务。艾美捷服务升级，全方位实验服务项目上线啦~

关键词：细胞分析试剂盒，胃蛋白酶/胃蛋白酶原活性测定试剂盒/胃蛋白酶/胃蛋白酶原活性测定试剂盒/胃蛋白酶/胃蛋白酶原活性测定试剂盒，待更新