脂肪酸酰胺水解酶/脂肪酸酰胺水解酶/脂肪酸酰胺水解酶

产品名称：脂肪酸酰胺水解酶/脂肪酸酰胺水解酶/脂肪酸酰胺水解酶-Fatty Acid Amide Hydrolase /Fatty Acid Amide Hydrolase /Fatty Acid Amide Hydrolase

产品货号：K434-100

产品规格：100assays

背景资料：待更新

保存建议：脂肪酸酰胺水解酶/脂肪酸酰胺水解酶/脂肪酸酰胺水解酶-Fatty Acid Amide Hydrolase /Fatty Acid Amide Hydrolase /Fatty Acid Amide Hydrolase -20°C

产品描述：Fatty Acid Amide Hydrolase (FAAH; EC: 3.5.1.99, Oleamide Hydrolase, Anandamide Amidohydrolase) is a mammalian integral membrane enzyme, and is a key regulator in lipid signaling. FAAH degrades naturally occurring fatty acid amides such as cannabinoid anandamide and oleamide, a sleep-inducing substance. In general, fatty acid amides are endogenous lipid ligands which activate the cannabinoid (CB) G-protein coupled receptors CB1 and CB2. CB1 and CB2 modulate physiological and behavioral processes such as pain, and anti-inflammation. Therefore, FAAH is crucial in the termination of fatty acid amide bioactive functions. Recent studies showed that blockage of FAAH activity led to increased fatty acid amides levels in nervous system and peripheral tissues. Thus, the study of FAAH and its potential inhibitors could develop novel treatment strategies for pain and central nerve system disorders due to the analgesic, anxiolytic and anti-inflammatory properties that are observed when elevated fatty acid amides are present in humans. In BioVision’s FAAH Assay Kit, FAAH hydrolyzes a non-fluorescent substrate releasing 7-amino-4-methylcoumarin (AMC), a fluorophore, which can be easily measured at Ex/Em= 360/465 nm. The kit provides a specific inhibitor that can be used to compensate for potential non-specfic background in unknown samples. The stable fluorescence signal is positively correlated to FAAH enzymatic activity in samples. The kit offers a rapid, simple, sensitive, reproducible assay and is suitable for detecting FAAH activity as low as 0.1 µU

点击：脂肪酸酰胺水解酶/脂肪酸酰胺水解酶/脂肪酸酰胺水解酶-Fatty Acid Amide Hydrolase /Fatty Acid Amide Hydrolase /Fatty Acid Amide Hydrolase 查看更详细产品说明，更多应用、储存、价格、货期等信息请致电垂询BioVision中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看每日生物评论网站。

BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的领路人.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理，艾美捷与BioVision一起为研究者们提供最好、崭新的细胞生物学研究工具而不断扩大产品及服务质量.

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关键词：细胞分析试剂盒，脂肪酸酰胺水解酶/脂肪酸酰胺水解酶/脂肪酸酰胺水解酶，待更新