谷氨酸脱氢酶抑制剂筛选试剂盒/谷氨酸脱氢酶抑制剂筛选试剂盒/

产品名称：谷氨酸脱氢酶抑制剂筛选试剂盒/谷氨酸脱氢酶抑制剂筛选试剂盒/谷氨酸脱氢酶抑制剂筛选试剂盒-Glutamate Dehydrogenase Inhibitor Screening Kit /Glutamate Dehydrogenase Inhibitor Screening Kit /Glutamate Dehydrogenase Inhibitor Screening Kit

产品货号：K185-100

产品规格：100assays

背景资料：待更新

保存建议：谷氨酸脱氢酶抑制剂筛选试剂盒/谷氨酸脱氢酶抑制剂筛选试剂盒/谷氨酸脱氢酶抑制剂筛选试剂盒-Glutamate Dehydrogenase Inhibitor Screening Kit /Glutamate Dehydrogenase Inhibitor Screening Kit /Glutamate Dehydrogenase Inhibitor Screening Kit -20°C

产品描述：Glutamate dehydrogenase (GDH) (1.4.1.2) is a hexameric enzyme that catalyzes the reversible conversion of glutamate to α-ketoglutarate and ammonia while reducing NAD+ to NADH. Glutamate can be converted to α-ketoglutarate by GDH and then fluxed into the TCA cycle where it can be used to support oxidative phosphorylation, production of lipids, or to replenish key intermediates such as oxaloacetate. It is a key enzyme in the glutamine metabolic pathway. Overexpression of GDH has been shown to promote cell proliferation, migration and invasion in several tumors such as colorectal cancer. The increased reliance on glutamine metabolism makes GDH a target for therapeutic intervention in cancer. GDH inhibitors have been shown to be toxic for cancer cells in vitro. In BioVision’s Glutamate Dehydrogenase inhibitor screening Kit, Glutamate is deaminated by GDH producing NADH, which converts a non-fluorescent probe to a fluorescent product in the presence of enzyme mix that is detected fluorometrically at Ex/Em = 535/587 nm. The kit provides a rapid, simple, sensitive plate based test, which is also suitable for high-throughput screening of GDH inhibitors.

点击：谷氨酸脱氢酶抑制剂筛选试剂盒/谷氨酸脱氢酶抑制剂筛选试剂盒/谷氨酸脱氢酶抑制剂筛选试剂盒-Glutamate Dehydrogenase Inhibitor Screening Kit /Glutamate Dehydrogenase Inhibitor Screening Kit /Glutamate Dehydrogenase Inhibitor Screening Kit 查看更详细产品说明，更多应用、储存、价格、货期等信息请致电垂询BioVision中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看每日生物评论网站。

BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的领路人.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理，艾美捷与BioVision一起为研究者们提供最好、崭新的细胞生物学研究工具而不断扩大产品及服务质量.

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关键词：细胞分析试剂盒，谷氨酸脱氢酶抑制剂筛选试剂盒/谷氨酸脱氢酶抑制剂筛选试剂盒/谷氨酸脱氢酶抑制剂筛选试剂盒，待更新