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- 保存条件:
在您收到艾美捷发出的【MMP 9】人源细胞表达的重组人基质金属蛋白酶9产品后,建议将其置于-20°C保存.
- 保质期:
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- 英文名:
Human CellExp MMP-9, human recombinant
- 库存:
人类CellExp MMP-9,人类重组
- 供应商:
艾美捷
- 规格:
50ug
产品名称:人类CellExp MMP-9,人类重组/人类CellExp MMP-9,人类重组/人类CellExp MMP-9,人类重组-Human CellExp MMP-9, human recombinant/Human CellExp MMP-9, human recombinant/Human CellExp MMP-9, human recombinant
产品货号:7246-50 产品规格:50ug 来源宿主:提供的【MMP 9】人源细胞表达的重组人基质金属蛋白酶9产品的来源为人胚胎肾HEK293细胞重组表达重组表达.
保存建议:人类CellExp MMP-9,人类重组/人类CellExp MMP-9,人类重组/人类CellExp MMP-9,人类重组-Human CellExp MMP-9, human recombinant/Human CellExp MMP-9, human recombinant/Human CellExp MMP-9, human recombinant在您收到艾美捷发出的【MMP 9】人源细胞表达的重组人基质金属蛋白酶9产品后,建议将其置于-20°C保存.
背景资料:Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive pro-proteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. Thrombospondins, intervertebral disc proteins, regulate the effective levels of matrix metalloproteinases (MMPs) 2 and 9, which are key effectors of ECM remodeling. Matrix metallopeptidase 9 (MMP-9), also known as 92 kDa type IV collagenase, 92 kDa gelatinase or gelatinase B (GELB), CLG4B, is secreted from neutrophils, macrophages, and a number of transformed cells, and is the most complex family member in terms of domain structure and regulation of its activity. Structurally, MMP9 maybe be divided into five distinct domains: a pro-domain which is cleaved upon activation, a gelatin binding domain consisting of three contiguous fibronectin type II units, a catalytic domain containing the zinc binding site, a proline rich linker region, and a carboxyl terminal hemopexin like domain. This enzyme degrades various substrates including gelatin, collagen types IV and V, and elastin. MMP9 is involved in a variety of autoimmune diseases such as systemic lupus erythematosus, rheumatoid arthritis, and multiple sclerosis, and be regarded as a potential therapeutic target.
点击:人类CellExp MMP-9,人类重组/人类CellExp MMP-9,人类重组/人类CellExp MMP-9,人类重组-Human CellExp MMP-9, human recombinant/Human CellExp MMP-9, human recombinant/Human CellExp MMP-9, human recombinant查看更详细产品说明,更多应用、储存、价格、货期等信息请致电垂询BioVision中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看每日生物评论网站。
BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的领路人.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理,艾美捷与BioVision一起为研究者们提供最好、崭新的细胞生物学研究工具而不断扩大产品及服务质量.
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关键词:Human CellExp MMP-9, human recombinant/Human CellExp MMP-9, human recombinant/Human CellExp MMP-9, human recombinant,人类CellExp MMP-9,人类重组/人类CellExp MMP-9,人类重组/人类CellExp MMP-9,人类重组,MMP 9
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文献和实验Assessment of Gelatinases (MMP-2 and MMP-9) by Gelatin Zymography
family, MMP-2 (gelatinase A) and MMP-9 (gelatinase B), due to their potent gelatin-degrading activity. This polyacrylamide gel electrophoresis-based method can provide a reliable assessment of the type of gelatinase, relative amount, and activation status
Human synovial cells in culture, particularly those obtained from patients with rheumatoid arthritis, secrete a number of matrix metalloproteinases (MMPs) into the culture medium. Enzymes secreted include collagenases (MMP-1, MMP-13
Use of EIA to Measure MMPs and TIMPs
the combination of a monoclonal antibody as the solid-phase with rabbit polyclonal antibody and horseradish peroxidase (HRP)-labeled donkey antirabbit gamma globulin as the second phase (2 ). EIAs for human MMP-9 were developed using MMP-9 specific polyclonal
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