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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
在您收到艾美捷发出的【MMP 1】人源细胞表达的重组人基质金属蛋白酶1产品后,建议将其置于-20°C保存.
- 保质期:
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- 英文名:
Human CellExp MMP-1, human recombinant
- 库存:
人类CellExp MMP-1,人类重组
- 供应商:
艾美捷
- 规格:
10ug
产品名称:人类CellExp MMP-1,人类重组/人类CellExp MMP-1,人类重组/人类CellExp MMP-1,人类重组-Human CellExp MMP-1, human recombinant/Human CellExp MMP-1, human recombinant/Human CellExp MMP-1, human recombinant
产品货号:7244-10 产品规格:10ug 来源宿主:提供的【MMP 1】人源细胞表达的重组人基质金属蛋白酶1产品的来源为人胚胎肾HEK293细胞重组表达重组表达.
保存建议:人类CellExp MMP-1,人类重组/人类CellExp MMP-1,人类重组/人类CellExp MMP-1,人类重组-Human CellExp MMP-1, human recombinant/Human CellExp MMP-1, human recombinant/Human CellExp MMP-1, human recombinant在您收到艾美捷发出的【MMP 1】人源细胞表达的重组人基质金属蛋白酶1产品后,建议将其置于-20°C保存.
背景资料:Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive pro-proteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. Thrombospondins, intervertebral disc proteins, regulate the effective levels of matrix metalloproteinases (MMPs) 2 and 9, which are key effectors of ECM remodeling. Matrix metalloproteinase-1 (MMP-1) also known as interstitial collagenase and fibroblast collagenase. MMP1 is expressed by fibroblasts, keratinocytes, endothelial cells, monocytes and macrophages. MMP-1 breaks down the interstitial collagens, types I, II, and III. MMP1 can degrade a broad range of substrates including types I, II, III, VII, VIII, and X collagens as well as casein, gelatin, myelin basic protein, L Selectin, proTNF, IL1β, IGFBP3, IGFBP5, pro MMP2 and pro MMP9.
点击:人类CellExp MMP-1,人类重组/人类CellExp MMP-1,人类重组/人类CellExp MMP-1,人类重组-Human CellExp MMP-1, human recombinant/Human CellExp MMP-1, human recombinant/Human CellExp MMP-1, human recombinant查看更详细产品说明,更多应用、储存、价格、货期等信息请致电垂询BioVision中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看每日生物评论网站。
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关键词:Human CellExp MMP-1, human recombinant/Human CellExp MMP-1, human recombinant/Human CellExp MMP-1, human recombinant,人类CellExp MMP-1,人类重组/人类CellExp MMP-1,人类重组/人类CellExp MMP-1,人类重组,MMP 1
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文献和实验Expression of Human Collagenase I (MMP-1) andTIMP-1 in a Baculovirus-Based Expression System
Resident cells of tissues are capable of secreting an array of structurally related zinc endopeptidases known as matrix metalloproteinases (MMPs). They initiate the degradation of the surrounding macromolecules of the extracellular matrix
Assessment of Gelatinases (MMP-2 and MMP-9) by Gelatin Zymography
family, MMP-2 (gelatinase A) and MMP-9 (gelatinase B), due to their potent gelatin-degrading activity. This polyacrylamide gel electrophoresis-based method can provide a reliable assessment of the type of gelatinase, relative amount, and activation status
Detecting Polymorphisms in MMP Genes
, have been estimated to exist approximately every 200–300 bp throughout the human genome (2 ). However, there are some sequence variants which affect the control of gene expression, the biosynthesis and transport of the gene product, or the function of the gene
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