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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
在您收到艾美捷发出的【Caspase 3 Pro】重组小鼠Caspase-3前体蛋白产品后,建议将其置于-70°C保存.
- 保质期:
根据订购时间与产品批次判定,欢迎联系艾美捷咨询确认
- 英文名:
Caspase-3 Proform, mouse recombinant
- 库存:
Caspase-3 Proform,小鼠重组
- 供应商:
艾美捷
- 规格:
5ug
产品名称:Caspase-3 Proform,小鼠重组/Caspase-3 Proform,小鼠重组/Caspase-3 Proform,小鼠重组-Caspase-3 Proform, mouse recombinant/Caspase-3 Proform, mouse recombinant/Caspase-3 Proform, mouse recombinant
产品货号:1183P-5 产品规格:5ug 来源宿主:提供的【Caspase 3 Pro】重组小鼠Caspase-3前体蛋白产品的来源为大肠杆菌中重组表达.
保存建议:Caspase-3 Proform,小鼠重组/Caspase-3 Proform,小鼠重组/Caspase-3 Proform,小鼠重组-Caspase-3 Proform, mouse recombinant/Caspase-3 Proform, mouse recombinant/Caspase-3 Proform, mouse recombinant在您收到艾美捷发出的【Caspase 3 Pro】重组小鼠Caspase-3前体蛋白产品后,建议将其置于-70°C保存.
背景资料:Caspase-3 (also know as CPP32, Yama and apopain) is a member of the caspase family of cysteine proteases. Caspase-3 exists in cells as an inactive 32 kDa proenzyme. Proteolytic processing of this inactive proenzyme generates the 17 kD and 12 kD subunits which, when assembled as a tetramer (a pair of heterodimers), form the active caspase. Cascades of caspase activation have been shown to be key signal-transducing events in apoptosis. Procaspase-3, like other procaspases with short N-terminal prodomains, is considered to be a downstream or “effector” enzyme. Pro-caspase-3 can be cleaved and activated by caspase-8 and –10 which are themselves activated through interaction with death ligand receptor/adapter protein complexes (e.g., Fas/FADD). Procaspase-3 is also processed by caspase-9, the apical caspase that is activated by binding to the Apaf-1/cytochrome c/ATP “apoptosome”. Thus, activation of procaspase-3 stands at a point of convergence for the two major types of apoptosis signaling pathways-those linked to cell surface death receptors and those linked to mitochondrial release of cytochrome c.The recombinant Procaspase-3 (1183P-5) is produced by expression of a human cDNA in E. coli. The purified protein is highly activatable by treatment with active recombinant caspase-8 (1088-25, -100). We routinely test the activation using 10-30 ng of the procaspase-3 treated with 0.1-0.5 units of the active recombinant caspase-8 in 100 ul of Reaction Buffer (1068-20) for 30 minutes. Activation of procaspase-3 can be monitored using the Caspase-3 Fluorometric and Colorimetric Assay Kits (K105 and K106).
点击:Caspase-3 Proform,小鼠重组/Caspase-3 Proform,小鼠重组/Caspase-3 Proform,小鼠重组-Caspase-3 Proform, mouse recombinant/Caspase-3 Proform, mouse recombinant/Caspase-3 Proform, mouse recombinant查看更详细产品说明,更多应用、储存、价格、货期等信息请致电垂询BioVision中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看每日生物评论网站。
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关键词:Caspase-3 Proform, mouse recombinant/Caspase-3 Proform, mouse recombinant/Caspase-3 Proform, mouse recombinant,Caspase-3 Proform,小鼠重组/Caspase-3 Proform,小鼠重组/Caspase-3 Proform,小鼠重组,Caspase 3
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文献和实验Mouse Strains and Genetic Nomenclature
., and Montagutelli, X. 2009. Genetic analysis of skull shape variation and morphological integration in the mouse using interspecific recombinant congenic strains between C57BL/6 and mice of the Mus spretus species. Evolution 63:2668‐2686
Culturing BG01V Human Embryonic Stem Cells with Mouse Embryonic Fibroblast (MEF)-Conditioned Media
(approximately 1.0 x 106 cells/60 mm plate) on the Cultrex BME coated plate in Conditioned Media containing 4 ng/mL of recombinant human FGF basic. Change the media daily. Monitor the cells for the desired confluency. Figure
The Mouse as Model System to Study Host‐Pathogen Interactions in Influenza A Infections
Abstract Table of Contents Materials Figures Literature Cited Abstract The mouse
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