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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Human recombinant Cathepsin E (Cat. No. 7842)
- 亚型:
Anti-Cathepsin E Antibody
- 形态:
Anti-Cathepsin E Antibody
- 保存条件:
-20°C
- 克隆性:
单克隆
- 标记物:
Anti-Cathepsin E Antibody
- 适应物种:
Western Blotting
- 保质期:
根据订购时间与产品批次判定,欢迎联系艾美捷咨询确认
- 抗原来源:
Human recombinant Cathepsin E (Cat. No. 7842)
- 目录编号:
Anti-Cathepsin E Antibody
- 级别:
Anti-Cathepsin E Antibody
- 库存:
Anti-Cathepsin E Antibody
- 供应商:
艾美捷
- 宿主:
待更新
- 应用范围:
Western Blotting
- 浓度:
Anti-Cathepsin E Antibody
- 靶点:
Anti-Cathepsin E Antibody
- 抗体英文名:
Anti-Cathepsin E Antibody
- 抗体名:
抗组织蛋白酶E抗体
- 规格:
100ug
产品名称:抗组织蛋白酶E抗体/抗组织蛋白酶E抗体/抗组织蛋白酶E抗体-Anti-Cathepsin E Antibody/Anti-Cathepsin E Antibody/Anti-Cathepsin E Antibody
产品货号:A1709-100-E 产品规格:100ug 应用类型:Western Blotting
保存建议:抗组织蛋白酶E抗体/抗组织蛋白酶E抗体/抗组织蛋白酶E抗体-Anti-Cathepsin E Antibody/Anti-Cathepsin E Antibody/Anti-Cathepsin E Antibody-20°C
背景资料:Cathepsin E (EC: 3.4.23.34) (CTSE) is an intracellular gastric aspartyl protease. It was originally identified as a cathepsin D-like acid protease. It is active in acidic conditions in a pH range from 2.5 to 5.5. In vitro experiments have identified several CTSE substrates including insulin beta chain, neurokinin, and FGF. Although the function of CTSE is not completely understood, it has been implicated in several physiological and pathological processes. CTSE is required for antigen presentation on class II MHC molecules. CTSE-deficient macrophages show abnormalities such as autophagy. Like many other cathepsins, CTSE has emerged as a therapy target for cancers, such as pancreatic ductal adenocarcinoma (PDAC). In addition to PDAC, CTSE is also overexpressed in gastric carcinomas and cervical and lung adenocarcinomas. The possible involvement of CTSE in neurodegeneration has also been reported. This protease has a specificity similar to that of pepsin A and cathepsin D. It is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is found in more than half of gastric cancers.
点击:抗组织蛋白酶E抗体/抗组织蛋白酶E抗体/抗组织蛋白酶E抗体-Anti-Cathepsin E Antibody/Anti-Cathepsin E Antibody/Anti-Cathepsin E Antibody查看更详细产品说明,更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看每日生物评论网站。
BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的领路人.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理,艾美捷与BioVision一起为研究者们提供最好、崭新的细胞生物学研究工具而不断扩大产品及服务质量.
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关键词:Anti-Cathepsin E Antibody/Anti-Cathepsin E Antibody/Anti-Cathepsin E Antibody,抗组织蛋白酶E抗体/抗组织蛋白酶E抗体/抗组织蛋白酶E抗体,Cathepsin E
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文献和实验E L I S A w i t h p l a t e l e t s
for 1 hour with a 1 :1000 dilution of rat IgG2 a anti-mouse kappa chain monoclonal antibody conjugated to horse-radish peroxidase (LO-MK1 , LO/IMEX) reveal with o-phenylenediamine dihydrochloride (OPD) in revelation solution. SOLUTIONS
Purifying and Measuring Immunoglobulin E (IgE) and Anti-IgE
of enzyme-linked immunosorbent assays (ELISAs) and monoclonal antibody technology has proven instrumental for advancing the science of Ig biology. IgE is of interest as it is the primary Ig responsible for allergic reactions ranging from allergic rhinitis
To fix, 1/10 volume of 37 formaldehyde is added to the culture, which is shaken for a further 40 minutes at room temperature. Cells are then recovered by centrifugation at 1400 X g for 2 minutes, and washed (i.e. gently resuspended then recovered
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