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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Full length protein
- 亚型:
RASSF1A Antibody
- 形态:
RASSF1A Antibody
- 保存条件:
-20°C
- 克隆性:
单克隆
- 标记物:
RASSF1A Antibody
- 适应物种:
WB, IH, IP
- 保质期:
根据订购时间与产品批次判定,欢迎联系艾美捷咨询确认
- 抗原来源:
Full length protein
- 目录编号:
RASSF1A Antibody
- 级别:
RASSF1A Antibody
- 库存:
RASSF1A Antibody
- 供应商:
艾美捷
- 宿主:
Mouse
- 应用范围:
WB, IH, IP
- 浓度:
RASSF1A Antibody
- 靶点:
RASSF1A Antibody
- 抗体英文名:
RASSF1A Antibody
- 抗体名:
RASSF1A抗体
- 规格:
100ug
产品名称:RASSF1A抗体/RASSF1A抗体/RASSF1A抗体-RASSF1A Antibody/RASSF1A Antibody/RASSF1A Antibody
产品货号:A1221-100-E 产品规格:100ug 应用类型:WB, IH, IP
保存建议:RASSF1A抗体/RASSF1A抗体/RASSF1A抗体-RASSF1A Antibody/RASSF1A Antibody/RASSF1A Antibody-20°C
背景资料:RASSF1A is one of the most epigenetically silenced gene in human cancers and an important negative regulator of NFkB activation and potential tumor suppressor. It is required for death receptor-dependent apoptosis. It also mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation. When associated with MOAP1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation. Isoform A interacts with CDC20, an activator of the anaphase-promoting complex, APC, resulting in the inhibition of APC activity and mitotic progression. RASSF1A inhibits proliferation by negatively regulating cell cycle progression at the level of G1/S-phase transition by regulating accumulation of cyclin D1 protein. Isoform C has been shown not to perform these roles; no function has been identified for this isoform. Isoform A disrupts interactions among MDM2, DAXX and USP7, thus contributing to the efficient activation of TP53 by promoting MDM2 self-ubiquitination in cell-cycle checkpoint control in response to DNA damage.
点击:RASSF1A抗体/RASSF1A抗体/RASSF1A抗体-RASSF1A Antibody/RASSF1A Antibody/RASSF1A Antibody查看更详细产品说明,更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看每日生物评论网站。
BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的领路人.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理,艾美捷与BioVision一起为研究者们提供最好、崭新的细胞生物学研究工具而不断扩大产品及服务质量.
艾美捷科技有限公司,通过提供完整的产品和服务体系、便利的客户关系和供应链管理,为生命科学研究工作者提供整体打包方案。我们的企业的核心价值观:“激情、敬业、学习、创新、合作、卓越”。激发我们内在的创造力,提供有竞争力的生物医学产品和服务,持续为客户创造最大价值是我们的企业使命。我们的企业愿景是成为受人尊重、世界知名的生物医学产品及服务供应商。艾美捷科技与国内外优秀的生物试剂供应商保持着密切的合作关系,目前已成为众多国际知名品牌的中国总代理或一级代理,主要包括:AmyJet、AAT Bioquest、Abnova、Agrisera、Biovision、Biosensis、Cayman Chemical、Caisson Labs、Cytoskeleton、CytoNiChe、Epigentek、Equitech-Bio、Hycult Biotech、Jackson、LifeSensors、ProSpec、Norgen Biotek、Mabtech、Matreya、iRegene、StressMarq、ImmunoReagents、SouthernBiotech、Origene、US Biological、Solis BioDyne等,可以在第一时间为用户提供最前沿的专业资讯、完备的产品及物流服务。艾美捷服务升级,全方位实验服务项目上线啦~
关键词:RASSF1A Antibody/RASSF1A Antibody/RASSF1A Antibody,RASSF1A抗体/RASSF1A抗体/RASSF1A抗体,RASSF1
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文献和实验Notes on Making Rat x Y3 Monoclonal Antibody Producing Hybridomas
Although Y3/Ag1.2.3 has its own myeloma light chain, their are numerous characteristics that make this a better parent line for making hybridomas than the 'Y0' chain loss variants or using NS0 to make rat x mouse hybrids. These are: a) Hybridomas
8.0) in clean 16x125mm polypropylene test tube. If needed, adjust pH to 8.0 using 0.5M carbonate buffer. 2. Prepare fresh, 1mg/mL of either NHS-FITC in DMSO or 1mg/mL NHS-LC-Biotin in DH2O. If FITC coupling, add 75uL of FITC/DMSO solution to Antibody
8.0) in clean 16x125mm polypropylene test tube. If needed, adjust pH to 8.0 using 0.5M carbonate buffer. 2. Prepare fresh, 1mg/mL of either NHS-FITC in DMSO or 1mg/mL NHS-LC-Biotin in DH2O. If FITC coupling, add 75uL of FITC/DMSO solution to Antibody
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