Caspase-10 Antibody [FAS-assoc
iated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE like Apoptotic Protease 4 ]/Caspase-10 Antibody [FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE like Apoptot- 询价
- BioVision
- 美国
- 6677-100
- 2025年07月13日
- Western blot: 1-4 µg
- 兔
- Western blot: 1-4 µg
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Human recombinant Caspase-10/a (Cat # 1090A)
- 亚型：
Caspase-10 Antibody [FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE like Apoptotic Protease 4 ]
- 形态：
Caspase-10 Antibody [FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE like Apoptotic Protease 4 ]
- 保存条件：
提供的Caspase-10抗体为无色溶液形式，产品浓度为0.5 mg/ml，溶解于包含有0.01 % BSA, 0.01 %硫柳汞,和50 %甘油的PBS缓冲液（pH 7.2）中.请在收到该Caspase-10抗体产品后，将其置于-20 °C冷冻保存，建议分装使用以避免反复冻融.
- 克隆性：
单克隆
- 标记物：
Caspase-10 Antibody [FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE like Apoptotic Protease 4 ]
- 适应物种：
Western blot: 1-4 µg
- 保质期：
根据订购时间与产品批次判定，欢迎联系艾美捷咨询确认
- 抗原来源：
Human recombinant Caspase-10/a (Cat # 1090A)
- 目录编号：
Caspase-10 Antibody [FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE like Apoptotic Protease 4 ]
- 级别：
Caspase-10 Antibody [FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE like Apoptotic Protease 4 ]
- 库存：
Caspase-10 Antibody [FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE like Apoptotic Protease 4 ]
- 供应商：
艾美捷
- 宿主：
兔
- 应用范围：
Western blot: 1-4 µg
- 浓度：
Caspase-10 Antibody [FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE like Apoptotic Protease 4 ]
- 靶点：
Caspase-10 Antibody [FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE like Apoptotic Protease 4 ]
- 抗体英文名：
Caspase-10 Antibody [FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE like Apoptotic Protease 4 ]
- 抗体名：
Caspase-10抗体
- 规格：
100ug
产品名称：Caspase-10抗体/Caspase-10抗体/Caspase-10抗体-Caspase-10 Antibody [FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE like Apoptotic Protease 4 ]/Caspase-10 Antibody [FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE like Apoptotic Protease 4 ]/Caspase-10 Antibody [FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE like Apoptotic Protease 4 ]
产品货号：6677-100-E 产品规格：100ug 应用类型：Western blot: 1-4 µg
保存建议：Caspase-10抗体/Caspase-10抗体/Caspase-10抗体-Caspase-10 Antibody [FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE like Apoptotic Protease 4 ]/Caspase-10 Antibody [FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE like Apoptotic Protease 4 ]/Caspase-10 Antibody [FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE like Apoptotic Protease 4 ]提供的Caspase-10抗体为无色溶液形式，产品浓度为0.5 mg/ml，溶解于包含有0.01 % BSA, 0.01 %硫柳汞,和50 %甘油的PBS缓冲液（pH 7.2）中.请在收到该Caspase-10抗体产品后，将其置于-20 °C冷冻保存，建议分装使用以避免反复冻融.
背景资料：Caspase family of cysteine proteases plays a key role in apoptosis. Caspase-10 is expressed in many tissues and cell lines. Similar to other caspases, caspase-10 is also synthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Four isoforms of caspase-10 have been identified: caspase-10a (Mch4), caspase-10b (FLICE2), caspase-10c and caspase-10d. They have the same prodomain but different mature large and small subdomains. Activated caspase-10 activates caspase-3,-4,-6,-7,-8, and –9, which are then involved in proteolytic cleavage of many cellular proteins. Caspase-10 has been shown to be involved in the Fas and TNFR1 - induced apoptosis.
点击：Caspase-10抗体/Caspase-10抗体/Caspase-10抗体-Caspase-10 Antibody [FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE like Apoptotic Protease 4 ]/Caspase-10 Antibody [FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE like Apoptotic Protease 4 ]/Caspase-10 Antibody [FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE like Apoptotic Protease 4 ]查看更详细产品说明，更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看每日生物评论网站。
BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的领路人.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理，艾美捷与BioVision一起为研究者们提供最好、崭新的细胞生物学研究工具而不断扩大产品及服务质量.
艾美捷科技有限公司，通过提供完整的产品和服务体系、便利的客户关系和供应链管理，为生命科学研究工作者提供整体打包方案。我们的企业的核心价值观：“激情、敬业、学习、创新、合作、卓越”。激发我们内在的创造力，提供有竞争力的生物医学产品和服务，持续为客户创造最大价值是我们的企业使命。我们的企业愿景是成为受人尊重、世界知名的生物医学产品及服务供应商。艾美捷科技与国内外优秀的生物试剂供应商保持着密切的合作关系，目前已成为众多国际知名品牌的中国总代理或一级代理，主要包括：AmyJet、AAT Bioquest、Abnova、Agrisera、Biovision、Biosensis、Cayman Chemical、Caisson Labs、Cytoskeleton、CytoNiChe、Epigentek、Equitech-Bio、Hycult Biotech、Jackson、LifeSensors、ProSpec、Norgen Biotek、Mabtech、Matreya、iRegene、StressMarq、ImmunoReagents、SouthernBiotech、Origene、US Biological、Solis BioDyne等，可以在第一时间为用户提供最前沿的专业资讯、完备的产品及物流服务。艾美捷服务升级，全方位实验服务项目上线啦~
关键词：Caspase-10 Antibody [FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE like Apoptotic Protease 4 ]/Caspase-10 Antibody [FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE like Apoptotic Protease 4 ]/Caspase-10 Antibody [FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE like Apoptotic Protease 4 ]，Caspase-10抗体/Caspase-10抗体/Caspase-10抗体，Caspase-10
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文献和实验to remove transformed cells and virus infected cells. Binding of FAS to oligimerized FasL on another cell activates apoptotic signaling through a cytoplasmic domain termed the death domain that interacts with signaling adaptors including FAF, FADD and DAX
Biochemical Analysis of the Native TRAIL Death-Inducing Signaling Complex
years. For the CD95 and the TRAIL-R1/R2 DISCs, it is now clear that the adaptor protein Fas-associated DD protein (FADD) forms part of these complexes and is necessary for recruitment of the pro-apoptotic signaling molecules caspase-8 and caspase-10
带有死亡结构域的Fas 结合蛋白 带有死亡结构域的Fas结合蛋白(Fas-associating protein with death domain，FADD)是分子质量为23kDa的胞质蛋白质。人类FADD基因编码区长约2．6kb，有2个外显子，其间被一长约2kb的内含子分隔。外显子1长286bp，编码N端诱导细胞凋亡所必须的死亡效应结构域(deatheffectdomain，DED)；外显子2长341bp，编码死亡结构域(DD)，此DD基因与Fas
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